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Basic information

CohesinDB ID: CDBG00011801

Gene Symbol: CYYR1

Ensembl ID: ENSG00000166265

Gene locus: chr21:26466215-26573286 Strand: -

Gene type: protein_coding

Double-evidenced cohesin related CRMs

Whether cohesin-related CRMs (double-evidenced): True

All evidenced type: Interaction,DEGs,

Regulatory cohesin (double-evidenced): chr21-25533153-25533484, chr21-25535719-25536333, chr21-25539425-25539987, chr21-25544195-25544755, chr21-25547302-25547456, chr21-25600851-25601124, chr21-25606719-25610187, chr21-25614176-25615182, chr21-25624549-25624749, chr21-25652526-25652691, chr21-25658229-25659074, chr21-25660159-25660645, chr21-25664270-25664549, chr21-25670626-25671144, chr21-25750080-25750495, chr21-25756342-25756628, chr21-25770235-25770898, chr21-25778080-25778847, chr21-25779288-25779695, chr21-25787871-25788223, chr21-25788822-25789364, chr21-25789892-25791705, chr21-25795113-25795355, chr21-25828364-25828688, chr21-25833846-25834090, chr21-25835857-25837162, chr21-25837509-25838288, chr21-25838795-25839584, chr21-25846197-25846384, chr21-25848451-25849082, chr21-25850382-25850871, chr21-25857068-25857674, chr21-25862118-25863437, chr21-25865445-25866261, chr21-25866908-25867564, chr21-25868924-25869531, chr21-25871333-25873005, chr21-25875158-25875785, chr21-25877272-25877556, chr21-25878883-25884507, chr21-25886456-25886884, chr21-25887111-25887606, chr21-25887958-25888558, chr21-25890135-25890660, chr21-25895168-25897778, chr21-25898579-25899047, chr21-25949635-25950151, chr21-25952178-25952242, chr21-25953149-25954885, chr21-25957155-25957888, chr21-25959897-25962359, chr21-25962876-25964940, chr21-25965954-25968091, chr21-25969014-25969348, chr21-25970446-25971016, chr21-25972490-25972729, chr21-26055116-26056355, chr21-26057470-26057741, chr21-26058637-26059126, chr21-26060627-26060916, chr21-26061415-26061729, chr21-26061934-26062607, chr21-26068005-26069153, chr21-26070638-26071594, chr21-26072693-26073278, chr21-26150217-26150652, chr21-26151334-26152383, chr21-26153595-26154542, chr21-26154777-26155253, chr21-26158881-26159268, chr21-26159924-26160609, chr21-26162072-26162427, chr21-26162939-26163160, chr21-26163946-26164899, chr21-26165409-26165563, chr21-26165938-26172090, chr21-26172443-26173621, chr21-26227867-26228375, chr21-26231319-26231639, chr21-26232405-26232965, chr21-26236206-26236625, chr21-26241048-26241459, chr21-26246206-26246745, chr21-26252748-26253550, chr21-26258758-26259007, chr21-26265323-26265680, chr21-26269376-26269901, chr21-26280655-26281366, chr21-26375270-26375569, chr21-26377212-26377465, chr21-26385630-26386225, chr21-26388039-26392190, chr21-26426603-26426761, chr21-26437290-26438175, chr21-26439370-26439560, chr21-26442974-26444624, chr21-26444843-26446180, chr21-26446388-26446877, chr21-26447728-26450082, chr21-26469516-26470634, chr21-26470936-26471471, chr21-26489802-26491360, chr21-26491759-26492502, chr21-26499281-26499944, chr21-26501095-26502315, chr21-26507039-26507391, chr21-26512271-26513860, chr21-26516805-26517164, chr21-26527113-26527235, chr21-26529571-26529884, chr21-26542226-26542363, chr21-26543512-26543793, chr21-26545511-26545777, chr21-26546651-26547189, chr21-26550230-26550784, chr21-26554333-26554888, chr21-26555706-26556025, chr21-26561447-26561737, chr21-26562684-26562870, chr21-26565280-26565546, chr21-26570205-26570607, chr21-26572401-26573661, chr21-26624988-26625410, chr21-26625735-26626595, chr21-26628878-26629023, chr21-26632886-26633405, chr21-26638242-26638348, chr21-26646461-26646646, chr21-26654803-26656127, chr21-26669172-26669887, chr21-26677932-26678184, chr21-26681492-26681815, chr21-26684363-26684507, chr21-26686016-26686591, chr21-26690085-26690451, chr21-26698349-26698770, chr21-26702109-26702704, chr21-26709227-26709736, chr21-26714761-26718662, chr21-26718980-26720367, chr21-26721013-26721255, chr21-26721627-26722108, chr21-28426062-28428543, chr21-28430646-28433389, chr21-28435933-28437451, chr21-28439119-28440662, chr21-28441650-28446617, chr21-28446900-28448101,

Co-expression with cohesin genes Rho = 0.3594 FDR = 0.0000
(Note: Cohesin does not need to 'co-express' with its regulated genes because expression of cohesin genes in conserved. The co-expression only provides addtional information)

Tissue specificity

Gene expression across tissues (TPM):

Tissue specificity of gene (Gini-coefficient): 0.501
0:Conserved; 1:Tissue-specific For all genes: quantile-25%: 0.26, quantile-50%: 0.36 'quantile-75%': 0.60

Cell Specificity of regulatory cohesin (1:Tissue-specific; 0:Conserved): 0.926
0:Conserved; 1:Tissue-specific. For all cohesin sites: quantile-25%: 0.82, quantile-50%: 0.86 'quantile-75%': 0.90

Cohesin-loop evidence

Whether has cohesin-loop: True

Involved cell types for loop evidence: MCF-7,HEK293T,REC-1,K-562,Kelly,H1-hESC,Motor-Neuron,HFF-hTERT,HAP1,HeLa-S3,H1-Trophectoderm,H9-hESC,H1-Mesenchymal,HUES64

Cohesin-loop type: HiChIP,HiC,Direct,ChIAPET

Cohesin-loop study: 4DNFI8649RQJ, 4DNFI3CFMRID, GSE95015, 4DNFIWZEN3FF, GSE43070, GSE116875, GSE118716, 4DNFIE8E4ANZ, GSE108787, 4DNFIB7QTIMH, GSE103148, 4DNFIW8TIFI5, 4DNFIBM714BP, 4DNFIV239W4L, GSE97394, 4DNFIE8T8JZ8, GSE52457, 4DNFIM2BMJ33, Direct, 4DNFI6XD6JAQ, 4DNFISPUVQHA, 4DNFI6JJQKFJ, GSE44267, 4DNFIQVMVRP6, ENCSR305RTT, 4DNFIVJ3IIQL, 4DNFIFI6NIKJ, 4DNFIDKJFK2S, GSE105028, 4DNFIDBIEXI7

Cohesin-loop subunit: Rad21,CTCF,Other,SMC1

Cohesin-DEGs evidence

Whether cohesin DEGs: True

Involved cell types for DEG evidence: MCF-10A,Keratinocytes

Cohesin-DEGs, number of studies: 3

Cohesin-DEGs, study: GSE83870,GSE101921

Cohesin-DEGs, subunit: SMC1,SA2,SMC3

eachgene

Deatailed information for gene ENSG00000166265