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Basic information

CohesinDB ID: CDBP00415332

Locus: chr21-25887958-25888558

Data sourse: ENCSR230ZWH, ENCSR917QNE

Cell type: Liver

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "4_Tx": 41%, "5_TxWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, HMG20A, HNF1A, FOXA1, RXRB, ATF3, THRB, PRDM1, ZNF273, CDX2, TEAD1, KLF6, ETV1, SNAI2, RCOR2, ESR1, OCA2, HNF1B, JUN, CTCF, BAF155, EP300, SOX5, SMC1, FOXA3, GATAD2A, NANOG, CHD8, ZSCAN5D, POU5F1, SRF, SAP130, ARID3A, HNF4G, ERG, HOXC5, ETS1, MYC, ONECUT1, HOMEZ, RAD21, GRHL3, RXRA, PROX1, NKX2-1, GABPA, NKX3-1, DNMT3B, NR2F6, NR3C1, CEBPB, EZH2, GABPB1, MIXL1, IRF1, GATA2, ZNF644, FLI1, NFIL3, ETV5, SMC1A, BCL6, CEBPA, NKX2-2, SOX13, ZFX, SMAD3, SMARCC1, RARA, ZNF384, CDK6, GR, DAXX, ARNT, ATF2, HMBOX1, SMAD4, FOS, MED1, ZEB1, TEAD3, PIAS1, C11orf30, RBM22, MAFK, NIPBL, SP1, HNF4A, ARID1A, POU2F3, ASH2L, FOXP1, SMC3, NCOR2, STAG1, ETV4, PPARG, FOXA2, NFATC1, PAF1, MAFF, FOXF1, HOXB13, ZKSCAN1, KDM1A, YY1, RELA, NEUROD1, JUNB, SP140, HIF1A, OTX2, GATA3, TAL1, MAX, GATA1, TLE3, KLF4, CEBPG, NR2F2, NEUROG2, TCF7L2, TP53, ELF3, PHF5A, KAT8, AR, PAX3-FOXO1, ZBTB26, BRD4, JUND, ZNF316, FOSL2

Target gene symbol (double-evidenced CRMs): CYYR1,ADAMTS1,APP,MRPL39

Function elements

Human SNPs: .

Number of somatic mutations (coding): 16

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000142192, ENSG00000166265, ENSG00000154734,

eachgene

Deatailed information for cohesin site CDBP00415332