- Basic information
- CohesinDB ID: CDBP00415327
- Locus: chr21-25875158-25875785
-
Data sourse: GSE116344, GSE67783
-
Cell type: RH4, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES,Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 54%,
"5_TxWk": 38%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RUNX1, CEBPB, REST, MYC, TRIM28, BCL11A, ZNF362, EZH2, GRHL3, TCF3, FEZF1, FOXA1, SPI1, ERG
- Target gene symbol (double-evidenced CRMs): MRPL39,CYYR1,APP,ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 13
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000142192,
ENSG00000166265,
ENSG00000154734,
- Related loop:
chr21:25600000-25625000~~chr21:25850000-25875000,
chr21:25600000-25625000~~chr21:25875000-25900000,
chr21:25606735-25609548~~chr21:25871125-25872823,
chr21:25606914-25609560~~chr21:25871146-25873235,
chr21:25750000-25775000~~chr21:25850000-25875000,
chr21:25850000-25875000~~chr21:26175000-26200000,
chr21:25850000-25875000~~chr21:26325000-26350000,
chr21:25850000-25875000~~chr21:26450000-26475000,
chr21:25850000-25875000~~chr21:26675000-26700000,
chr21:25850000-25875000~~chr21:26700000-26725000,
chr21:25871157-25873150~~chr21:26715252-26718261,
chr21:25875000-25900000~~chr21:25975000-26000000,
chr21:25875000-25900000~~chr21:26050000-26075000,
chr21:25875000-25900000~~chr21:26150000-26175000,
chr21:25875000-25900000~~chr21:26175000-26200000,
chr21:25875000-25900000~~chr21:26325000-26350000,
chr21:25875000-25900000~~chr21:26375000-26400000,
chr21:25875000-25900000~~chr21:26400000-26425000,
chr21:25875000-25900000~~chr21:26525000-26550000,
chr21:25875000-25900000~~chr21:26675000-26700000,
chr21:25875000-25900000~~chr21:26700000-26725000,
chr21:25875000-25900000~~chr21:26825000-26850000,
chr21:25875000-25900000~~chr21:28725000-28750000,
chr21:25880592-25882759~~chr21:26168595-26171726,
chr21:25880592-25882759~~chr21:26715468-26718051,
chr21:25880643-25882866~~chr21:26000836-26002126,
chr21:25880643-25882866~~chr21:26169947-26171806,
chr21:25880643-25882866~~chr21:26715421-26718120,
chr21:25880719-25882754~~chr21:26168603-26171485,
chr21:25880719-25882754~~chr21:26716644-26718024,
chr21:25880755-25882952~~chr21:26168541-26171786,
chr21:25880755-25882952~~chr21:26715348-26718310,
chr21:25880758-25882873~~chr21:26715355-26718381,
chr21:25880762-25882939~~chr21:26168567-26172542,
chr21:25880762-25882939~~chr21:26715356-26718205,
chr21:25880770-25883137~~chr21:26168491-26171741,
chr21:25880770-25883137~~chr21:26715200-26718356,
chr21:25880785-25882961~~chr21:26168597-26171877,
chr21:25880785-25882961~~chr21:26715447-26718081,