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Basic information

CohesinDB ID: CDBP00415951

Locus: chr21-28430646-28433389

Data sourse: ENCSR000EFJ, GSE67783, GSE111913, ENCSR000HPG, GSE206145, GSE206145-NatGen2015, GSE165895

Cell type: RPE, Fibroblast, IMR-90, RT-112, HSPC, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.933

Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 36% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 68%, "5_TxWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, FOXA2, POU5F1, TOP2A, SOX2, ESR2, FOXA1, FOXF1, HOXB13, ZNF792, ERG, RELA, CREBBP, ATF3, RUNX2, MYC, GATA4, PBX4, GATA3, PRDM9, MAX, NKX3-1, NRIP1, FOS, MED1, TLE3, KLF4, ESRRA, NR3C1, CEBPB, PIAS1, ESR1, ZNF334, SETDB1, BAF155, BHLHE40, AR, GATA2, BRD4, FOXP1, ZNF528

Target gene symbol (double-evidenced CRMs): LINC00113,CYYR1,ADAMTS1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 11

Related genes and loops

Related gene: ENSG00000166265, ENSG00000154734, ENSG00000225298,

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Deatailed information for cohesin site CDBP00415951