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Basic information

CohesinDB ID: CDBP00415357

Locus: chr21-25957155-25957888

Data sourse: ENCSR000EFJ, ENCSR000HPG, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, GSE116344

Cell type: RPE, Fibroblast, RH4, IMR-90, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: Mau2,SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES,Intragenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 61%, "4_Tx": 15%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PAX7, PGR, CEBPA, NKX2-2, POU5F1, TOP2A, SOX2, NME2, SIN3A, SMAD3, FOXA1, HOXB13, HOXC5, RELA, NEUROD1, JUNB, RUNX2, MYC, RAD21, PBX4, ARNT, OTX2, GATA3, TAL1, PBX3, MAX, STAT3, FOS, MED1, NR3C1, CEBPB, CEBPD, OCA2, NCOA1, ZNF334, NFKB1, JUN, RBM22, TCF12, AR, HDAC2, REST, FLI1, BRD4, JUND, NR1H3, MRTFB, FOSL2

Target gene symbol (double-evidenced CRMs): APP,GABPA,CYYR1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 64

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154727, ENSG00000142192, ENSG00000166265,

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Deatailed information for cohesin site CDBP00415357