Deatailed information for cohesin site CDBP00415526


Check detailed explainations here

  • Basic information
  • CohesinDB ID: CDBP00415526
  • Locus: chr21-26625735-26626595
  • Data sourse: GSE206145, GSE206145-NatGen2015, GSE86191
  • Cell type: RPE, Fibroblast, HCT-116
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 1% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.967
  • Subunit: SA1,Rad21,SA2
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True
  • Compartment: 42% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): non-Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "15_Quies": 71%, "9_Het": 17%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: RUNX1, TRP47, TRIM25, POU2F2, SMC1A, FOXA2, MYCN, POU5F1, CRY1, SOX2, ZFX, RUNX1T1, XBP1, KDM4C, ZBTB48, WT1, ZSCAN5A, TBL1X, TET2, ERG, YY1, RELA, OGG1, ATF3, SP140, GRHL3, TCF4, STAT3, TP63, ZNF143, PLAG1, TEAD1, EZH2, LMO2, OCA2, CTCF, SPI1, AR, REST, PTBP1, HEXIM1, FLI1, HSF1, NOTCH3, BRD4, TCF3, MAZ, AATF, HCFC1R1, SMC3, STAG1
  • Target gene symbol (double-evidenced CRMs): CYYR1
  • Function elements
  • Human SNPs: .
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 19
  • Related genes and loops

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