- Basic information
- CohesinDB ID: CDBP00415298
- Locus: chr21-25756342-25756628
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Data sourse: GSE101921, ENCSR153HNT
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Cell type: K-562, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SA1,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 61%,
"4_Tx": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, FOXA2, POU4F2, XBP1, GTF2B, ZSCAN16, FOXA1, ERG, RELA, ZNF384, NOTCH1, MYC, RUNX2, ZNF362, PRDM1, GABPA, TAL1, XRCC5, ZNF143, FOS, STAT5B, ESR1, ZNF22, CTCF, JUN, SPI1, AR, IRF1, IRF4, BRD4, CLOCK, ZIM3, STAG2
- Target gene symbol (double-evidenced CRMs): APP,MRPL39,GABPA,CYYR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 2
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25575000-25600000~~chr21:25750000-25775000,
chr21:25600000-25625000~~chr21:25750000-25775000,
chr21:25750000-25775000~~chr21:25850000-25875000,
chr21:25750000-25775000~~chr21:25950000-25975000,
chr21:25750000-25775000~~chr21:26150000-26175000,
chr21:25750000-25775000~~chr21:26400000-26425000,
chr21:25750000-25775000~~chr21:26450000-26475000,
chr21:25750000-25775000~~chr21:26525000-26550000,
chr21:25750000-25775000~~chr21:29050000-29075000,