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Basic information

CohesinDB ID: CDBP00415538

Locus: chr21-26698349-26698770

Data sourse: GSE116344, ENCSR198ZYJ, ENCSR404BPV

Cell type: Neurons-H1, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 42% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 78%, "14_ReprPCWk": 18%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: ZSCAN5D, NKX2-2, FOXA2, POU5F1, XBP1, FOXA1, SMARCA4, HIF1A, ATF2, MAFB, NKX3-1, SPIB, HAND2, ZEB1, NEUROG2, EZH2, EBF3, CTCF, EP300, REST, ATF7, JUND, PDX1

Target gene symbol (double-evidenced CRMs): CYYR1,GABPA,APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 2

Related genes and loops

Related gene: ENSG00000154727, ENSG00000142192, ENSG00000166265,

eachgene

Deatailed information for cohesin site CDBP00415538