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Basic information

CohesinDB ID: CDBP00415303

Locus: chr21-25788822-25789364

Data sourse: GSE67783, GSE206145, GSE206145-NatGen2015, GSE120943, ENCSR153HNT

Cell type: RPE, Fibroblast, Monocytes, K-562, HSPC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SA2,SMC1

CTCF binding site: CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 56%, "14_ReprPCWk": 41%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RELA, PLAG1, RFX1, EZH2, ARNT, RNF2, DUX4, RAD51, NOTCH3, GRHL3, HIF1A, USF2, XBP1, MAX, USF1, STAG1

Target gene symbol (double-evidenced CRMs): CYYR1,APP,JAM2

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 6

Related genes and loops

Related gene: ENSG00000154721, ENSG00000142192, ENSG00000166265,

eachgene

Deatailed information for cohesin site CDBP00415303