- Basic information
- CohesinDB ID: CDBP00415333
- Locus: chr21-25890135-25890660
-
Data sourse: GSE206145, ENCSR230ZWH, GSE86191
-
Cell type: RPE, Liver, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 49%,
"4_Tx": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, RELA, NR2F2, RAD21, ZFX, ESR1, RXRA, FOXA1, SPI1, RBM22, SP1
- Target gene symbol (double-evidenced CRMs): CYYR1,MRPL39,APP,ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000142192,
ENSG00000166265,
ENSG00000154734,
- Related loop:
chr21:25600000-25625000~~chr21:25875000-25900000,
chr21:25875000-25900000~~chr21:25975000-26000000,
chr21:25875000-25900000~~chr21:26050000-26075000,
chr21:25875000-25900000~~chr21:26150000-26175000,
chr21:25875000-25900000~~chr21:26175000-26200000,
chr21:25875000-25900000~~chr21:26325000-26350000,
chr21:25875000-25900000~~chr21:26375000-26400000,
chr21:25875000-25900000~~chr21:26400000-26425000,
chr21:25875000-25900000~~chr21:26525000-26550000,
chr21:25875000-25900000~~chr21:26675000-26700000,
chr21:25875000-25900000~~chr21:26700000-26725000,
chr21:25875000-25900000~~chr21:26825000-26850000,
chr21:25875000-25900000~~chr21:28725000-28750000,
chr21:25886689-25887960~~chr21:26168542-26171691,
chr21:25886700-25888011~~chr21:26715421-26718120,
chr21:25886797-25887944~~chr21:26715196-26718405,
chr21:25894856-25897119~~chr21:26168541-26171786,
chr21:25894856-25897119~~chr21:26715348-26718310,
chr21:25894872-25896862~~chr21:25999375-26002832,
chr21:25894872-25896862~~chr21:26715196-26718405,
chr21:25895002-25896873~~chr21:26168572-26171752,
chr21:25895048-25897116~~chr21:26168461-26171694,
chr21:25895048-25897116~~chr21:26715193-26718542,
chr21:25895093-25897256~~chr21:26000596-26002821,
chr21:25895093-25897256~~chr21:26031390-26033174,
chr21:25895093-25897256~~chr21:26715477-26718366,
chr21:25895098-25896866~~chr21:26715200-26718356,
chr21:25895145-25896737~~chr21:26169947-26171806,
chr21:25895145-25896737~~chr21:26715421-26718120,
chr21:25895157-25897132~~chr21:26715317-26718206,
chr21:25895183-25896791~~chr21:26168600-26171765,
chr21:25895184-25896718~~chr21:25999508-26002814,
chr21:25895184-25896849~~chr21:26168597-26171877,
chr21:25895184-25896849~~chr21:26715447-26718081,
chr21:25895199-25896667~~chr21:26170075-26171770,
chr21:25895223-25896749~~chr21:26170145-26171780,
chr21:25895288-25896659~~chr21:26031859-26033130,