- Basic information
- CohesinDB ID: CDBP00415533
- Locus: chr21-26677932-26678184
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Data sourse: GSE206145-NatGen2015, GSE86191
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Cell type: Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 92%,
"14_ReprPCWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU2F2, SMARCA2, FOXA2, SOX2, ZFX, ZBTB48, FOXA1, SMARCC1, RELA, CREBBP, EOMES, ARNT, GRHL3, GATA3, EZH2, ESR1, NUP98-HOXA9, AR, GATA6, SIX2, FLI1
- Target gene symbol (double-evidenced CRMs): GABPA,APP,CYYR1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 1
- Related genes and loops
- Related gene:
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25775000-25800000~~chr21:26675000-26700000,
chr21:25850000-25875000~~chr21:26675000-26700000,
chr21:25875000-25900000~~chr21:26675000-26700000,
chr21:26125000-26150000~~chr21:26675000-26700000,
chr21:26175000-26200000~~chr21:26675000-26700000,
chr21:26250000-26275000~~chr21:26650000-26675000,
chr21:26250000-26275000~~chr21:26675000-26700000,
chr21:26375000-26400000~~chr21:26650000-26675000,
chr21:26375000-26400000~~chr21:26675000-26700000,
chr21:26525000-26550000~~chr21:26650000-26675000,
chr21:26525000-26550000~~chr21:26675000-26700000,