- Basic information
- CohesinDB ID: CDBP00415281
- Locus: chr21-25670626-25671144
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Data sourse: ENCSR230ZWH, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, ENCSR917QNE
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Cell type: RPE, Liver, Fibroblast, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,Rad21,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, NANOG, SMARCA2, MYCN, SOX2, ZFX, WT1, MAFF, HOXB13, SMARCC1, TWIST1, KDM1A, YY1, RELA, JUNB, ATF3, MYC, NFIC, SMARCA4, NEUROD1, RAD21, PBX4, OTX2, GATA3, STAT3, MAX, PBX3, TAL1, FOS, CDK8, NR3C1, JMJD1C, CEBPB, NR2F2, CEBPD, ESR1, CTCF, TCF12, JUN, SP1, EP300, GSPT2, MAFK, AR, FLI1, JUND, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): ADAMTS5,CYYR1,JAM2
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 3
- Number of somatic mutations (non-coding): 0
- Related genes and loops