- Basic information
- CohesinDB ID: CDBP00415363
- Locus: chr21-25972490-25972729
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Data sourse: GSE101921
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Cell type: HMEC, MCF-10A, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"5_TxWk": 42%,
"4_Tx": 40%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, ZNF384, TOP2A, PRDM1, SETDB1, ZNF350, PAX5, RBM22, STAG2, LMO1
- Target gene symbol (double-evidenced CRMs): GABPA,CYYR1,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25600000-25625000~~chr21:25975000-26000000,
chr21:25750000-25775000~~chr21:25950000-25975000,
chr21:25775000-25800000~~chr21:25950000-25975000,
chr21:25875000-25900000~~chr21:25975000-26000000,
chr21:25950000-25975000~~chr21:26050000-26075000,
chr21:25950000-25975000~~chr21:26075000-26100000,
chr21:25950000-25975000~~chr21:26125000-26150000,
chr21:25950000-25975000~~chr21:26150000-26175000,
chr21:25950000-25975000~~chr21:26250000-26275000,
chr21:25950000-25975000~~chr21:26375000-26400000,
chr21:25950000-25975000~~chr21:26525000-26550000,
chr21:25950000-25975000~~chr21:26800000-26825000,
chr21:25975000-26000000~~chr21:26100000-26125000,
chr21:25975000-26000000~~chr21:26150000-26175000,