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Basic information

CohesinDB ID: CDBP00415297

Locus: chr21-25750080-25750495

Data sourse: GSE116344, GSE83726, GSE73207

Cell type: TF-1, RH4

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 67% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "5_TxWk": 49%, "4_Tx": 37%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PAX7, MYCN, RUNX1T1, ERG, PBX1, NOTCH1, RUNX3, RAD21, GABPA, SMAD4, ZNF189, JMJD1C, MYB, KMT2A, EVI1, MYOD1, TCF12, RBM22, BCL11A, LMO1, PAX3-FOXO1, GATA2, SIX2, NOTCH3, BRD4, TCF3

Target gene symbol (double-evidenced CRMs): APP,MRPL39,GABPA,CYYR1

Function elements

Human SNPs: .

Number of somatic mutations (coding): 2

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154727, ENSG00000142192, ENSG00000166265,

eachgene

Deatailed information for cohesin site CDBP00415297