- Basic information
- CohesinDB ID: CDBP00415544
- Locus: chr21-26721627-26722108
-
Data sourse: GSE116344, GSE120943, GSE98367
-
Cell type: RH4, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 90%,
"14_ReprPCWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: DUX4, NME2, AHR, XBP1
- Target gene symbol (double-evidenced CRMs): ADAMTS1,CYYR1,MRPL39,GABPA,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
ENSG00000154734,
- Related loop:
chr21:25600000-25625000~~chr21:26700000-26725000,
chr21:25600000-25625000~~chr21:26725000-26750000,
chr21:25734147-25737065~~chr21:26715239-26718238,
chr21:25775000-25800000~~chr21:26700000-26725000,
chr21:25789414-25791324~~chr21:26715348-26718310,
chr21:25789469-25791355~~chr21:26715196-26718405,
chr21:25789485-25791180~~chr21:26715356-26718205,
chr21:25789502-25791503~~chr21:26715239-26718238,
chr21:25789503-25791490~~chr21:26715252-26718261,
chr21:25789504-25791193~~chr21:26715280-26718256,
chr21:25789567-25791545~~chr21:26715396-26718303,
chr21:25825000-25850000~~chr21:26700000-26725000,
chr21:25825000-25850000~~chr21:26725000-26750000,
chr21:25850000-25875000~~chr21:26700000-26725000,
chr21:25862108-25863550~~chr21:26715501-26718096,
chr21:25871157-25873150~~chr21:26715252-26718261,
chr21:25875000-25900000~~chr21:26700000-26725000,
chr21:25880592-25882759~~chr21:26715468-26718051,
chr21:25880643-25882866~~chr21:26715421-26718120,
chr21:25880719-25882754~~chr21:26716644-26718024,
chr21:25880755-25882952~~chr21:26715348-26718310,
chr21:25880758-25882873~~chr21:26715355-26718381,
chr21:25880762-25882939~~chr21:26715356-26718205,
chr21:25880770-25883137~~chr21:26715200-26718356,
chr21:25880785-25882961~~chr21:26715447-26718081,
chr21:25880794-25882895~~chr21:26715448-26718086,
chr21:25880795-25883103~~chr21:26714832-26718268,
chr21:25880802-25883195~~chr21:26715193-26718542,
chr21:25880806-25883113~~chr21:26715204-26718284,
chr21:25880813-25882766~~chr21:26715409-26718024,
chr21:25880821-25883172~~chr21:26715280-26718256,
chr21:25880823-25883149~~chr21:26715242-26718467,
chr21:25880831-25882882~~chr21:26715317-26718206,
chr21:25880833-25882973~~chr21:26715347-26718278,
chr21:25880871-25883139~~chr21:26715160-26718522,
chr21:25880873-25883193~~chr21:26715252-26718261,
chr21:25880878-25883186~~chr21:26715477-26718366,
chr21:25880879-25883157~~chr21:26715196-26718405,
chr21:25880911-25882804~~chr21:26715538-26718232,
chr21:25880921-25883079~~chr21:26715396-26718303,
chr21:25880943-25882795~~chr21:26715485-26718222,
chr21:25881104-25882779~~chr21:26715351-26718059,
chr21:25881130-25882858~~chr21:26715239-26718238,
chr21:25886700-25888011~~chr21:26715421-26718120,
chr21:25886797-25887944~~chr21:26715196-26718405,
chr21:25894856-25897119~~chr21:26715348-26718310,
chr21:25894872-25896862~~chr21:26715196-26718405,
chr21:25895048-25897116~~chr21:26715193-26718542,
chr21:25895093-25897256~~chr21:26715477-26718366,
chr21:25895098-25896866~~chr21:26715200-26718356,
chr21:25895145-25896737~~chr21:26715421-26718120,
chr21:25895157-25897132~~chr21:26715317-26718206,
chr21:25895184-25896849~~chr21:26715447-26718081,
chr21:26000000-26025000~~chr21:26700000-26725000,
chr21:26010694-26012200~~chr21:26715347-26718278,
chr21:26010769-26012247~~chr21:26715196-26718405,
chr21:26075000-26100000~~chr21:26700000-26725000,
chr21:26150000-26175000~~chr21:26700000-26725000,
chr21:26168536-26171703~~chr21:26715160-26718522,
chr21:26168542-26171691~~chr21:26714717-26718289,
chr21:26168542-26171800~~chr21:26715396-26718303,
chr21:26168566-26171735~~chr21:26715280-26718256,
chr21:26168567-26172542~~chr21:26715356-26718205,
chr21:26168579-26171721~~chr21:26714841-26717171,
chr21:26168586-26171752~~chr21:26715190-26718539,
chr21:26168591-26172572~~chr21:26715252-26718261,
chr21:26175000-26200000~~chr21:26700000-26725000,
chr21:26177658-26178878~~chr21:26715348-26718310,
chr21:26275000-26300000~~chr21:26700000-26725000,
chr21:26325000-26350000~~chr21:26700000-26725000,
chr21:26375000-26400000~~chr21:26700000-26725000,
chr21:26400000-26425000~~chr21:26700000-26725000,
chr21:26475000-26500000~~chr21:26700000-26725000,
chr21:26500000-26525000~~chr21:26700000-26725000,
chr21:26550000-26575000~~chr21:26700000-26725000,
chr21:26575000-26600000~~chr21:26700000-26725000,
chr21:26700000-26725000~~chr21:26825000-26850000,
chr21:26700000-26725000~~chr21:28725000-28750000,
chr21:26714841-26717171~~chr21:27422531-27425391,
chr21:26715447-26718081~~chr21:27700496-27701861,
chr21:26725000-26750000~~chr21:26825000-26850000,
chr21:26725000-26750000~~chr21:28025000-28050000,
chr21:26725000-26750000~~chr21:28725000-28750000,