- Basic information
- CohesinDB ID: CDBP00415320
- Locus: chr21-25850382-25850871
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Data sourse: ENCSR198ZYJ, ENCSR404BPV
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Cell type: Neurons-H1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
67% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 72%,
"14_ReprPCWk": 19%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, BCL6, FOXA2, NKX2-2, SOX2, GTF2B, FOXA1, ERG, RELA, NEUROD1, BMI1, SMARCA4, RFX1, GR, GATA4, GRHL3, OTX2, GABPA, TAL1, TP63, SOX10, MITF, NR3C1, EZH2, TP73, CTCF, BCL11A, AR, NCOR1
- Target gene symbol (double-evidenced CRMs): MRPL39,GABPA,CYYR1,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25600000-25625000~~chr21:25825000-25850000,
chr21:25600000-25625000~~chr21:25850000-25875000,
chr21:25750000-25775000~~chr21:25850000-25875000,
chr21:25825000-25850000~~chr21:26450000-26475000,
chr21:25825000-25850000~~chr21:26700000-26725000,
chr21:25825000-25850000~~chr21:26725000-26750000,
chr21:25850000-25875000~~chr21:26175000-26200000,
chr21:25850000-25875000~~chr21:26325000-26350000,
chr21:25850000-25875000~~chr21:26450000-26475000,
chr21:25850000-25875000~~chr21:26675000-26700000,
chr21:25850000-25875000~~chr21:26700000-26725000,