- Basic information
- CohesinDB ID: CDBP00415519
- Locus: chr21-26570205-26570607
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Data sourse: GSE101921, GSE94872, ENCSR230ZWH, ENCSR917QNE
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Cell type: Liver, HUVEC, HCAEC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 41%,
"14_ReprPCWk": 21%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: TRIM25, SOX2, XBP1, FOXA1, SUZ12, TFAP4, ZNF90, ATF3, CTCFL, CHD7, CBFB, TP63, ZNF736, TRIM28, ETV1, ESR1, OCA2, MED26, JUN, CTCF, TCF12, EP300, RYBP, E2F6, E2F1, SMC1, TEAD4, GTF2F1, PDX1, TFAP2C, EED, JARID2, NANOG, CHD8, BRD1, ZSCAN5D, POU5F1, MYCN, BRD3, KDM4C, ZBTB48, STAT1, SRF, TBP, ERG, OGG1, ETS1, MYC, SMARCA4, KDM4A, RAD21, GRHL3, RXRA, STAT3, PRDM14, NFE2, NR3C1, SRSF3, KMT2A, CREB1, EZH2, PHF8, ZHX2, SPI1, HDAC2, GATA2, INTS13, SIX2, FLI1, MXI1, HCFC1R1, MRTFB, PTBP1, RUNX1, SMC1A, EZH2phosphoT487, NKX2-2, SIRT6, SIN3A, ZFX, SMAD3, TET2, RARA, ZNF384, RUNX2, BACH1, ETV6, MAFB, CHD1, CDK8, CEBPD, TAF7, SETDB1, USF1, SP1, BCL11A, REST, ARID1A, ASH2L, PCGF2, CTBP2, BCOR, FOXP1, AATF, SMC3, STAG1, STAG2, TRP47, FOXA2, TBL1X, RBBP5, EBF1, NFATC1, ZNF207, WT1, HOXB13, KDM1A, YY1, RELA, ZNF19, NEUROD1, SP140, HIF1A, PCGF1, OTX2, TAL1, MAX, MAF1, GATA1, ZNF143, AGO2, CBX2, NR2F2, KDM5B, TP53, BRD2, T, AR, TAF1, RXR, HEXIM1, HSF1, NOTCH3, BRD4, JUND, MAZ, ZNF316
- Target gene symbol (double-evidenced CRMs): CYYR1,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 22
- Number of somatic mutations (non-coding): 11
- Related genes and loops