- Basic information
- CohesinDB ID: CDBP00415536
- Locus: chr21-26686016-26686591
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Data sourse: GSE62063
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Cell type: Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: NIPBL
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"14_ReprPCWk": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: SOX2, XBP1, FOXA1, ATF3, PRDM1, DPF1, ZSCAN4, MITF, MAF, ZNF629, ELF1, TRIM28, ETV1, KLF10, OCA2, USF2, ZNF577, JUN, TCF12, BAF155, MNT, SIX5, IRF4, RAD51, E2F1, PDX1, RBPJ, POU2F2, MYCN, CDK7, TOP2A, ZBTB17, DUX4, STAT1, BAHD1, TBP, ERG, ZBTB21, HOXC5, ETS1, MYC, TOP1, NKX2-1, GABPA, STAT3, NKX3-1, KMT2A, CREB1, DDX21, GABPB1, SPI1, IRF1, INTS13, GATA2, FLI1, HCFC1, ATF1, RUNX1, THAP11, NKX2-2, ZNF335, SIN3A, PRDM10, NOTCH1, SP3, ARNT, ATF2, ZNF518A, SUPT5H, FOS, CDK8, MED1, ZEB1, MYB, PIAS1, SETDB1, USF1, MAFK, ATF7, FOXA2, CREM, CHD2, GTF2B, ZNF574, CDK9, YY1, RELA, JUNB, TCF4, HIF1A, MAX, SPIB, ZNF143, HAND2, KLF4, NCOA3, TP53, MYOD1, BRD2, ELF3, TAF1, EGLN2, BRD4, JUND, CLOCK, ZNF316, FOSL2
- Target gene symbol (double-evidenced CRMs): CYYR1,GABPA,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154727,
ENSG00000142192,
ENSG00000166265,
- Related loop:
chr21:25775000-25800000~~chr21:26675000-26700000,
chr21:25850000-25875000~~chr21:26675000-26700000,
chr21:25875000-25900000~~chr21:26675000-26700000,
chr21:26125000-26150000~~chr21:26675000-26700000,
chr21:26175000-26200000~~chr21:26675000-26700000,
chr21:26250000-26275000~~chr21:26675000-26700000,
chr21:26375000-26400000~~chr21:26675000-26700000,
chr21:26525000-26550000~~chr21:26675000-26700000,