- Basic information
- CohesinDB ID: CDBP00415291
- Locus: chr21-25714159-25714449
-
Data sourse: GSE132649, GSE67783, GSE86191
-
Cell type: T-47D, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"5_TxWk": 55%,
"15_Quies": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: RELA, SOX2, ZFX, XBP1, WT1
- Target gene symbol (double-evidenced CRMs): JAM2,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 30
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000154721,
- Related loop:
chr21:25100000-25125000~~chr21:25700000-25725000,
chr21:25400000-25425000~~chr21:25700000-25725000,
chr21:25425000-25450000~~chr21:25700000-25725000,
chr21:25450000-25475000~~chr21:25700000-25725000,
chr21:25575000-25600000~~chr21:25700000-25725000,
chr21:25600000-25625000~~chr21:25700000-25725000,
chr21:25606634-25609370~~chr21:25707698-25709437,
chr21:25606701-25609531~~chr21:25707358-25710489,
chr21:25606733-25609495~~chr21:25707675-25710605,
chr21:25606735-25609548~~chr21:25707427-25710615,
chr21:25606746-25609376~~chr21:25707582-25709297,
chr21:25606776-25609578~~chr21:25707372-25710258,
chr21:25606789-25609441~~chr21:25707688-25710567,
chr21:25606790-25609462~~chr21:25707708-25709351,
chr21:25606798-25609451~~chr21:25707713-25709464,
chr21:25606803-25609752~~chr21:25707420-25710495,
chr21:25606809-25609470~~chr21:25707720-25709296,
chr21:25606813-25609482~~chr21:25707421-25709301,
chr21:25606813-25609514~~chr21:25707387-25710588,
chr21:25606813-25609539~~chr21:25707400-25709389,
chr21:25606813-25609564~~chr21:25707391-25709523,
chr21:25606815-25609560~~chr21:25707341-25710526,
chr21:25606816-25609496~~chr21:25707510-25709485,
chr21:25606818-25609406~~chr21:25707731-25709697,
chr21:25606824-25609539~~chr21:25707688-25710613,
chr21:25606830-25609546~~chr21:25707223-25709539,
chr21:25606834-25609470~~chr21:25707558-25709528,
chr21:25606865-25609546~~chr21:25707695-25710621,
chr21:25606869-25609453~~chr21:25707877-25710598,
chr21:25606871-25609531~~chr21:25707660-25710535,
chr21:25606873-25609559~~chr21:25707322-25709495,
chr21:25606880-25609493~~chr21:25707645-25709314,
chr21:25606885-25609476~~chr21:25707878-25709259,
chr21:25606887-25609611~~chr21:25708003-25709470,
chr21:25606894-25609602~~chr21:25708009-25709440,
chr21:25606899-25609820~~chr21:25707427-25709461,
chr21:25606920-25609753~~chr21:25708007-25709432,
chr21:25606927-25609505~~chr21:25708020-25709433,
chr21:25606943-25609746~~chr21:25708004-25709487,
chr21:25606945-25609755~~chr21:25708023-25709409,
chr21:25606952-25609468~~chr21:25707804-25709308,
chr21:25606963-25609577~~chr21:25707939-25710591,
chr21:25606981-25609372~~chr21:25707950-25709246,
chr21:25606981-25609574~~chr21:25707674-25709566,
chr21:25607045-25609461~~chr21:25707835-25709504,
chr21:25607052-25609346~~chr21:25707738-25709299,
chr21:25707427-25710615~~chr21:25800672-25802523,
chr21:25707695-25710621~~chr21:25800757-25802438,