- Basic information
- CohesinDB ID: CDBP00415274
- Locus: chr21-25642332-25642777
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Data sourse: GSE206145-GSE177045
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Cell type: MCF-7
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 39%,
"14_ReprPCWk": 33%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, FOXO1, NEUROD1, GATA2, FOXA2, ELF1, GATA4, SCRT2, SOX2, MYC, TOP2A, ZSCAN16, DUX4, OTX2, ATF2, FOXA1, ELF3, ZNF316
- Target gene symbol (double-evidenced CRMs): ADAMTS1,ATP5PF,GABPA,JAM2,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 12
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000154721,
ENSG00000154723,
ENSG00000154727,
ENSG00000142192,
ENSG00000154734,
- Related loop:
chr21:25606733-25609495~~chr21:25639158-25640825,
chr21:25606735-25609548~~chr21:25638240-25641048,
chr21:25606790-25609462~~chr21:25639349-25640533,
chr21:25606798-25609451~~chr21:25639345-25640775,
chr21:25606813-25609564~~chr21:25639067-25640965,
chr21:25606899-25609820~~chr21:25639037-25640766,
chr21:25625000-25650000~~chr21:25725000-25750000,
chr21:25625000-25650000~~chr21:25775000-25800000,
chr21:25625000-25650000~~chr21:26150000-26175000,
chr21:25625000-25650000~~chr21:26825000-26850000,
chr21:25625000-25650000~~chr21:28050000-28075000,