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Basic information

CohesinDB ID: CDBP00415599

Locus: chr21-26945787-26946495

Data sourse: GSE105028, GSE116344, GSE206145-NatGen2015, GSE83726

Cell type: Fibroblast, RH4, H9-hESC

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 2% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.967

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 31%, "7_Enh": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, PAX7, PGR, CHD8, NANOG, CEBPA, NKX2-2, MYCN, ZNF263, SOX2, ZFX, POU4F2, XBP1, POU5F1, ZBTB48, STAT1, FOXF1, ZNF205, MEF2C, CDK9, RING1B, SMARCC1, TWIST1, ERG, RELA, OGG1, NEUROD1, CDK6, SMARCA4, RAD21, CHD7, ARNT, HIF1A, GRHL3, RXRA, OTX2, ATF2, GABPA, ZNF143, CDK8, MITF, PRDM14, MED1, ARNTL, VDR, MYOG, CEBPB, KMT2A, ETV1, TFAP2C, PPARG, EZH2, ESR1, ZNF334, MYOD1, CTCF, BRD2, ARRB1, SPI1, TFAP2A, AR, PAX3-FOXO1, IRF4, ATF7, NOTCH3, BRD4, BCOR, RBPJ

Target gene symbol (double-evidenced CRMs): JAM2,ADAMTS1,ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 9

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154721, ENSG00000154734, ENSG00000154736,

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Deatailed information for cohesin site CDBP00415599