- Basic information
- CohesinDB ID: CDBP00415572
- Locus: chr21-26824624-26825033
-
Data sourse: GSE206145, GSE206145-NatGen2015, GSE111913, GSE86191
-
Cell type: RPE, Fibroblast, HCT-116, RT-112
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SA2,SMC1
-
CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 88%,
"9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: ZBTB48, ZFX, SP140
- Target gene symbol (double-evidenced CRMs): ADAMTS5,APP,GABPA,LINC00113,JAM2,ATP5PF,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000154721,
ENSG00000154723,
ENSG00000154727,
ENSG00000142192,
ENSG00000154736,
ENSG00000225298,
- Related loop:
chr21:23400000-23425000~~chr21:26825000-26850000,
chr21:25025000-25050000~~chr21:26825000-26850000,
chr21:25300000-25325000~~chr21:26800000-26825000,
chr21:25375000-25400000~~chr21:26825000-26850000,
chr21:25575000-25600000~~chr21:26800000-26825000,
chr21:25600000-25625000~~chr21:26825000-26850000,
chr21:25625000-25650000~~chr21:26825000-26850000,
chr21:25725000-25750000~~chr21:26825000-26850000,
chr21:25775000-25800000~~chr21:26800000-26825000,
chr21:25875000-25900000~~chr21:26825000-26850000,
chr21:25950000-25975000~~chr21:26800000-26825000,
chr21:26150000-26175000~~chr21:26800000-26825000,
chr21:26150000-26175000~~chr21:26825000-26850000,
chr21:26375000-26400000~~chr21:26800000-26825000,
chr21:26700000-26725000~~chr21:26825000-26850000,
chr21:26725000-26750000~~chr21:26825000-26850000,
chr21:26800000-26825000~~chr21:28225000-28250000,
chr21:26800000-26825000~~chr21:28725000-28750000,
chr21:26800000-26825000~~chr21:28950000-28975000,
chr21:26825000-26850000~~chr21:26925000-26950000,
chr21:26825000-26850000~~chr21:27550000-27575000,
chr21:26825000-26850000~~chr21:27675000-27700000,
chr21:26825000-26850000~~chr21:27700000-27725000,
chr21:26825000-26850000~~chr21:28025000-28050000,
chr21:26825000-26850000~~chr21:28050000-28075000,
chr21:26825000-26850000~~chr21:28200000-28225000,
chr21:26825000-26850000~~chr21:28225000-28250000,
chr21:26825000-26850000~~chr21:28325000-28350000,
chr21:26825000-26850000~~chr21:28425000-28450000,
chr21:26825000-26850000~~chr21:28500000-28525000,
chr21:26825000-26850000~~chr21:28525000-28550000,
chr21:26825000-26850000~~chr21:28575000-28600000,
chr21:26825000-26850000~~chr21:28625000-28650000,
chr21:26825000-26850000~~chr21:28725000-28750000,
chr21:26825000-26850000~~chr21:28750000-28775000,
chr21:26825000-26850000~~chr21:28925000-28950000,
chr21:26825000-26850000~~chr21:28950000-28975000,
chr21:26825000-26850000~~chr21:30175000-30200000,