- Basic information
- CohesinDB ID: CDBP00415285
- Locus: chr21-25691774-25692309
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Data sourse: GSE206145, GSE67783, GSE86191
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Cell type: RPE, HCT-116, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,SA1,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
61% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 67%,
"5_TxWk": 25%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, FOXA2, KDM4C, ZFX, XBP1, ZBTB48, ZSCAN5A, WT1, ZFP37, PBX2, HOXB13, RELA, SMARCA4, GATA4, SP140, NR3C1, CEBPB, NEUROG2, NR2F1, ESR1, PKNOX1, SETDB1, PHOX2B, JUN, CTCF, ZHX2, EP300, BHLHE40, FLI1, BRD4, SMC3, STAG1
- Target gene symbol (double-evidenced CRMs): JAM2
- Function elements
- Human SNPs: Longitudinal_change_in_brain_amyloid_plaque_burden
- Number of somatic mutations (coding): 15
- Number of somatic mutations (non-coding): 4
- Related genes and loops