- Basic information
- CohesinDB ID: CDBP00415228
- Locus: chr21-25453162-25454024
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Data sourse: GSE206145-NatGen2015
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Cell type: Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.989
- Subunit: Mau2,SA1,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 87%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, RELA, VDR, NR3C1, CHD8, RUNX2, NFIC, PBX4, BRD4, SMAD3, PBX3, FOXA1, FOXP1, GATA3, JUND, TEAD4, TCF12, EP300, FOSL2
- Target gene symbol (double-evidenced CRMs): JAM2,ATP5PF
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 7
- Related genes and loops
- Related gene:
ENSG00000154721,
ENSG00000154723,
- Related loop:
chr21:14525000-14550000~~chr21:25450000-25475000,
chr21:17775000-17800000~~chr21:25450000-25475000,
chr21:25420786-25422730~~chr21:25455832-25458166,
chr21:25423746-25424928~~chr21:25455834-25458451,
chr21:25425000-25450000~~chr21:25550000-25575000,
chr21:25425000-25450000~~chr21:25700000-25725000,
chr21:25450000-25475000~~chr21:25550000-25575000,
chr21:25450000-25475000~~chr21:25700000-25725000,
chr21:25450000-25475000~~chr21:29225000-29250000,
chr21:25450000-25475000~~chr21:38225000-38250000,
chr21:25455832-25458166~~chr21:25501013-25503266,
chr21:25455834-25458451~~chr21:25486329-25488255,
chr21:25455834-25458451~~chr21:25572455-25574658,
chr21:25458986-25460259~~chr21:25486634-25488226,