Deatailed information for cohesin site CDBP00415229

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  • Basic information
  • CohesinDB ID: CDBP00415229
  • Locus: chr21-25456209-25458906
  • Data sourse: GSE38395, GSE93080, ENCSR000EAC, ENCSR000DZP, GSE98367, GSE155324, GSE206145, GSE206145-NatGen2015, GSE62063, ENCSR000BMY, GSE120943, GSE103477, GSE111537, GSE50893
  • Cell type: MDM, GM2610, GM19240, B-cell, RPE, GM2630, Fibroblast, hLCL, GM2255, GM18526, SNYDER, Monocytes, Lymphoblast, GM12878, GM12891, GM2588, THP-1, Macrophage, Ramos, GM12892, GM19238, OCI-AML-3
  • DNA Sequence of binding site: UCSC hg38
  • Cohesin category
  • Peak occupancy ratio: 10% samples have this site.
  • Cell specificity (0: conserved, 1: cell type specific): 0.756
  • Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
  • CTCF binding site: CTCF CTCF motif: False
  • Genomic location: Intergenic
  • 3D genome
  • TAD boundary: Boundary
  • Chromatin hubs: Hub
  • Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True
  • Compartment: 35% Hi-C samples shows Compartment A
  • Cis-regulatory elements
  • Enhancer (Fantom5): Enhancer
  • Super enhancer (SEdb): False
  • Chromatin annotation: "15_Quies": 55%, "7_Enh": 24%,
    Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
  • Co-bound Transcriptional factors: FOXO1, FOSL1, PGR, CBX5, E2F7, NME2, XBP1, FOXA1, SUZ12, HDGF, TSC22D4, BMI1, NFIC, RUNX3, PRDM1, CBFB, PAX5, BACH2, MAF, JMJD1C, ELF1, BCLAF1, TEAD1, KLF6, ZNF217, MLL, TP73, HNF1B, OCA2, USF2, CTCF, JUN, SND1, EP300, TCF12, BAF155, DPF2, IRF4, RFX5, TRIM24, RAD51, TEAD4, KMT2B, RBPJ, EED, POU2F2, BRD3, TOP2A, MTA2, DUX4, STAT1, SRF, NBN, ARID3A, TBP, ERG, CHD4, ZNF597, NFKB2, ETS1, MYC, RAD21, GRHL3, RXRA, BATF3, GABPA, STAT3, IKZF1, CD74, VDR, NR3C1, CEBPB, STAT5B, KMT2A, CREB1, TBL1XR1, EZH2, SPI1, IRF1, HDAC2, GATA2, DRAP1, MXI1, SMARCA5, RELB, RUNX1, CIITA, SMC1A, BCL6, AFF4, ZFX, SMAD3, ERG3, TRIM22, SMARCC1, ZNF18, MEF2A, CREBBP, ZBTB2, ZNF384, IRF2, RUNX2, CDK6, ARNT, DAXX, PBX4, BACH1, ATF2, PRDM9, FOXM1, ETV6, PBX3, FOS, CDK8, MED1, ZEB1, PML, CEBPD, MYB, PIAS1, SMAD1, ZMYM3, STAT5A, ZNF22, MAFK, BCL11A, SP1, NIPBL, REST, ATF7, ASH2L, TCF3, FOXP1, PRDM6, STAT2, NCOR2, MLLT1, NFATC3, MEF2B, ZNF207, MTA3, CREM, EBF1, NFATC1, E2F8, CHD2, MEIS1, GTF2B, ZBED1, MEF2C, TCF7, CDK9, BCL3, YY1, RELA, TARDBP, NEUROD1, JUNB, ISL1, TCF4, SKIL, HIF1A, ZFP36, OTX2, GATA3, BATF, TAL1, MAX, SPIB, KLF4, ZNF592, NR2F2, NR2F1, ZNF687, PKNOX1, TP53, MED, ZNF334, NFKB1, PHOX2B, TBX21, BHLHE40, AR, TAF1, RXR, IKZF2, BRD4, JUND, CLOCK, ZNF24, AHR, FOSL2
  • Target gene symbol (double-evidenced CRMs): ATP5PF,JAM2
  • Function elements
  • Human SNPs: Parasitemia_in_Tripanosoma_cruzi_seropositivity
  • Number of somatic mutations (coding): 0
  • Number of somatic mutations (non-coding): 14
  • Related genes and loops
  • Related gene: ENSG00000154721, ENSG00000154723,
  • Related loop: chr21:14525000-14550000~~chr21:25450000-25475000, chr21:17775000-17800000~~chr21:25450000-25475000, chr21:25420786-25422730~~chr21:25455832-25458166, chr21:25423746-25424928~~chr21:25455834-25458451, chr21:25450000-25475000~~chr21:25550000-25575000, chr21:25450000-25475000~~chr21:25700000-25725000, chr21:25450000-25475000~~chr21:29225000-29250000, chr21:25450000-25475000~~chr21:38225000-38250000, chr21:25455832-25458166~~chr21:25501013-25503266, chr21:25455834-25458451~~chr21:25486329-25488255, chr21:25455834-25458451~~chr21:25572455-25574658, chr21:25458986-25460259~~chr21:25486634-25488226,
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