- Basic information
- CohesinDB ID: CDBP00415567
- Locus: chr21-26810912-26811585
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Data sourse: GSE206145, GSE116344, GSE83726
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Cell type: RPE, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 79%,
"5_TxWk": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: CDK9-HEXIM1, FOXA2, ZNF263, MYCN, SIN3A, SS18, XBP1, SMAD3, PAX6, NEUROD1, GATA4, EOMES, RAD21, LHX2, GRHL3, ARNT, OTX2, GATA3, PRDM9, MAX, PAX5, GATA1, MED1, VDR, MYOG, CEBPB, MYOD1, CTCF, MAFK, BHLHE40, PAX3-FOXO1, GATA6, AR, GATA2, ZNF182, BRD4, MYF5, AHR
- Target gene symbol (double-evidenced CRMs): MRPL39,APP,GABPA
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000154727,
ENSG00000142192,
- Related loop:
chr21:25300000-25325000~~chr21:26800000-26825000,
chr21:25575000-25600000~~chr21:26800000-26825000,
chr21:25775000-25800000~~chr21:26800000-26825000,
chr21:25950000-25975000~~chr21:26800000-26825000,
chr21:26150000-26175000~~chr21:26800000-26825000,
chr21:26375000-26400000~~chr21:26800000-26825000,
chr21:26800000-26825000~~chr21:28225000-28250000,
chr21:26800000-26825000~~chr21:28725000-28750000,
chr21:26800000-26825000~~chr21:28950000-28975000,
chr21:26815238-26816923~~chr21:27700282-27702347,