- Basic information
- CohesinDB ID: CDBP00415545
- Locus: chr21-26731078-26733640
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Data sourse: ENCSR230ZWH, GSE131606, ENCSR000BUC, ENCSR917QNE, GSE115602, GSE93080, GSE67783, GSE86191, GSE101921, GSE51234, ENCSR198ZYJ, GSE112028, GSE130135, ENCSR199XBQ, GSE94872, ENCSR895JMI, GSE118494, ENCSR000EEG, GSE105004, ENCSR054FKH, GSE83726, ENCSR000ECS, GSE38411, ENCSR000BLD, GSE104888, GSE126634, GSE103477, GSE108869, GSE143937, GSE138405, GSE135093, GSE106870, ENCSR193NSH, GSE206145, GSE85526, ENCSR000ECE, ENCSR767DFK, ENCSR984DZW, GSE55407, ENCSR000BTQ, GSE129526, ENCSR000BLY, GSE121355, GSE111537, GSE25021, GSE122299, GSE115250, GSE76893, ENCSR000BMY, ENCSR000EHX, GSE97394, GSE131956, GSE110061, ENCSR000HPG, GSE111913, ENCSR335RKQ, ENCSR000EDE, GSE50893, GSE206145-GSE177045, GSE72082, ENCSR501LQA, GSE116868, ENCSR404BPV, GSE105028, ENCSR000EDW, GSE165895, ENCSR000EFJ, ENCSR000BTU, ENCSR000DZP, ENCSR000BKV, GSE152721, GSE206145-NatGen2015, GSE138105, ENCSR703TNG, GSE116344, GSE98367, ENCSR768DOX, ENCSR879KXD, ENCSR000BLS, ENCSR000EHW, ENCSR981FDC, ENCSR167MTG, ENCSR944ZCT, GSE68388, GSE126990
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Cell type: MDM, RH4, GM2610, SLK, CVB-hiPSC, GM19240, HSPC, Liver, GP5d, TC-32, HuCC-T1, H9-hESC, RPE, GM2630, HMEC, Fibroblast, HEKn, Ishikawa, GM12890, HeLa-S3, GM2255, IMR-90, BCBL-1, K-562, GM18486, DKO, HFFc6, H1-hESC, SNYDER, MB157, GM12878, GM12891, GM2588, GBM39, SK-N-SH, GM19239, HeLa-Tet-On, RT-112, THP-1, GM19099, HUES64, Macrophage, GM12892, MCF-7, Hela-Kyoto, HCT-116, HEK293T, Hep-G2, Neurons-H1, A-549, HUVEC, HCAEC, HeLa, OCI-AML-3, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 40% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.378
- Subunit: SA1,Rad21,SMC1,SMC3ac,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
42% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 57%,
"7_Enh": 24%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: AR, SFPQ, RELA, SUZ12, CHD8, ZFX, GRHL3, KLF12, TAL1, STAT3, CTCF, TBP, TFAP2C
- Target gene symbol (double-evidenced CRMs): ADAMTS1,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 17
- Related genes and loops