- Basic information
- CohesinDB ID: CDBP00415206
- Locus: chr21-25342463-25343340
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Data sourse: GSE206145-NatGen2015, GSE50893
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Cell type: Fibroblast, GM18486
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA1,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
35% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 78%,
"5_TxWk": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: POU5F1, TOP2A, SOX2, HNF1A, DUX4, SMAD3, FOXA1, RELA, RUNX2, MYC, NFIC, CHD7, LHX2, ARNT, GATA3, STAT3, PBX3, FOXM1, GATA1, FOS, MED1, VDR, CEBPB, ZNF334, SETDB1, ELF3, TCF12, USF1, EP300, JUN, CTCF, REST, JUND, BRD4, TEAD4, FOSL2
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 12
- Related genes and loops