- Basic information
- CohesinDB ID: CDBP00415375
- Locus: chr21-26009756-26011796
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Data sourse: ENCSR000BLD, GSE206145-GSE177045, GSE72082, ENCSR000BLY, GSE105028, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, GSE67783, ENCSR703TNG, GSE116344, ENCSR000EEG, ENCSR000BLS, ENCSR000EHW, ENCSR000ECE, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, GSE129526, ENCSR000EDE, GSE83726, GSE50893
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Cell type: RH4, GM2610, GM19240, Liver, H9-hESC, GM2630, Ishikawa, HeLa-S3, GM18486, H1-hESC, SNYDER, GM12878, GM2588, SK-N-SH, GM19239, HUES64, MCF-7, GM12892, HCT-116, Hep-G2, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 12% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.767
- Subunit: SA1,Rad21,SMC1,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 64%,
"15_Quies": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, PGR, POU2F2, FOXA2, TOP2A, FOXA1, HOXB13, ERG, RELA, OGG1, GATA4, SMARCA4, GRHL3, GATA3, ZNF189, ZNF143, TLE3, NR3C1, TEAD1, NEUROG2, PIAS1, RBM22, BAF155, AR, GATA2, SIX2, BRD4, FOXP1
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 272
- Number of somatic mutations (non-coding): 0
- Related genes and loops