- Basic information
- CohesinDB ID: CDBP00415371
- Locus: chr21-26000893-26001794
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Data sourse: ENCSR000BLD, ENCSR230ZWH, GSE72082, ENCSR000BLY, GSE105028, GSE111537, GSE131606, GSE25021, ENCSR917QNE, ENCSR000BTU, GSE93080, ENCSR000DZP, ENCSR000EAC, GSE67783, ENCSR000BKV, GSE86191, GSE138405, GSE101921, GSE116344, GSE94872, GSE98367, ENCSR000BLS, GSE206145, ENCSR000ECE, GSE62063, ENCSR000BMY, ENCSR000EHX, GSE97394, ENCSR000BTQ, ENCSR167MTG, GSE110061, GSE129526, GSE83726, GSE126990, GSE50893
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Cell type: RH4, GM10847, GM19240, Liver, H9-hESC, RPE, GM2630, Ishikawa, GM12890, GM2255, K-562, GM18486, DKO, GM18526, H1-hESC, SNYDER, GM18505, GM12878, GM12891, SK-N-SH, GM19239, GM19193, Macrophage, HUES64, MCF-7, GM12892, Ramos, Hela-Kyoto, HCT-116, Hep-G2, HUVEC, HCAEC, GM19238, OCI-AML-3, HSPC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 14% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.611
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 69%,
"15_Quies": 14%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, CDX2, AR, HOXB13, PAF1, EZH2, XBP1, CTCF, MAFF, MAFK, FOXA1, C11orf30, SETDB1, LEO1, RBM22, ZNF143, AGO2, ZNF316
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 48
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000142192,
- Related loop:
chr21:25600000-25625000~~chr21:25975000-26000000,
chr21:25600000-25625000~~chr21:26000000-26025000,
chr21:25606914-25609560~~chr21:26000712-26002239,
chr21:25875000-25900000~~chr21:25975000-26000000,
chr21:25880643-25882866~~chr21:26000836-26002126,
chr21:25880833-25882973~~chr21:25999508-26002814,
chr21:25880878-25883186~~chr21:26000596-26002821,
chr21:25880879-25883157~~chr21:25999375-26002832,
chr21:25880888-25882763~~chr21:26000649-26002298,
chr21:25894872-25896862~~chr21:25999375-26002832,
chr21:25895093-25897256~~chr21:26000596-26002821,
chr21:25895184-25896718~~chr21:25999508-26002814,
chr21:25975000-26000000~~chr21:26100000-26125000,
chr21:25975000-26000000~~chr21:26150000-26175000,
chr21:26000000-26025000~~chr21:26325000-26350000,
chr21:26000000-26025000~~chr21:26700000-26725000,