- Basic information
- CohesinDB ID: CDBP00415376
- Locus: chr21-26012489-26013187
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Data sourse: GSE206145, GSE116344, GSE67783, GSE68388
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Cell type: RPE, RH4, HSPC, HuCC-T1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SA1,Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 72%,
"15_Quies": 22%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, ZSCAN5D, EBF1, TOP2A, ZFX, XBP1, ZBTB48, ZSCAN5A, SMAD3, FOXA1, RELA, ZBTB2, ZNF384, SMAD2, ZFP64, ZNF362, RAD21, ARNT, KLF6, SNAI2, SCRT2, ESR1, TBX5, EBF3, CTCF, RBM22, STAG1
- Target gene symbol (double-evidenced CRMs): MRPL39,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 16
- Number of somatic mutations (non-coding): 0
- Related genes and loops