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Basic information

CohesinDB ID: CDBP00415570

Locus: chr21-26816961-26817766

Data sourse: GSE62063

Cell type: Ramos

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.989

Subunit: NIPBL

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 41% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): True

Chromatin annotation: "15_Quies": 92%, "5_TxWk": 6%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, ZNF391, ZSCAN5C, SOX2, NME2, XBP1, FOXA1, SUZ12, ZNF274, NFIC, CTCFL, ZBTB44, CHD7, ZNF444, ZSCAN4, TRIM28, SNAI2, ESR1, ZNF561, CTCF, JUN, EP300, BAF155, PAX8, ZNF410, ZNF528, SMC1, TEAD4, PDX1, GLIS1, NANOG, POU5F1, MYCN, RUNX1T1, ZSCAN21, ZSCAN5A, STAT1, SRF, DDX5, ERG, MYC, SMARCA4, RFX1, TSHZ1, RAD21, ZNF2, GRHL3, RXRA, NKX2-1, GABPA, STAT3, UBN1, NKX3-1, NFE2, ZNF639, NR3C1, CEBPB, CREB1, KLF8, ZHX2, ZNF664, GATA2, FLI1, MRTFB, SMC1A, CBX1, NKX2-2, SMAD3, REPIN1, ZFP37, ZNF770, ZNF654, TRIM22, SMARCC1, ZNF18, PRDM10, ZBTB2, ZNF35, GATA4, OSR2, PBX4, NRF1, ZEB2, MAFB, ZNF10, MED1, ZEB1, ZXDB, SCRT2, PIAS1, NUP98-HOXA9, SP1, HNF4A, REST, ZHX1, HOXA9, PHIP, FOXP1, PRDM6, SMC3, ZNF34, STAG1, FOXA2, SS18, ZNF692, ZSCAN16, MAFF, FOXF1, HOXB13, KDM1A, YY1, NEUROD1, BRG1, HIF1A, OTX2, MAX, TLE3, KLF4, BCL11B, SP7, TP53, ZNF334, PHOX2B, T, BRD2, AR, ZNF324, EGLN2, ZBTB42, ZNF280D, HSF1, NCOR1, BRD4, SCRT1, ZSCAN23, BRCA1

Target gene symbol (double-evidenced CRMs): GABPA,APP,MRPL39

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 3

Related genes and loops

Related gene: ENSG00000154719, ENSG00000154727, ENSG00000142192,

eachgene

Deatailed information for cohesin site CDBP00415570