- Basic information
- CohesinDB ID: CDBP00415435
- Locus: chr21-26176450-26178042
-
Data sourse: GSE86191, GSE116344, GSE206145-NatGen2015, GSE83726
-
Cell type: RH4, Fibroblast, HCT-116
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 46%,
"7_Enh": 26%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: HDAC2, ATF3, SNAI2, CHD7, DUX4, PHOX2B
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000142192,
- Related loop:
chr21:24925000-24950000~~chr21:26150000-26175000,
chr21:25350000-25375000~~chr21:26150000-26175000,
chr21:25400000-25425000~~chr21:26150000-26175000,
chr21:25575000-25600000~~chr21:26150000-26175000,
chr21:25575000-25600000~~chr21:26175000-26200000,
chr21:25600000-25625000~~chr21:26150000-26175000,
chr21:25600000-25625000~~chr21:26175000-26200000,
chr21:25606813-25609539~~chr21:26168567-26171752,
chr21:25606813-25609564~~chr21:26168596-26171705,
chr21:25625000-25650000~~chr21:26150000-26175000,
chr21:25750000-25775000~~chr21:26150000-26175000,
chr21:25775000-25800000~~chr21:26150000-26175000,
chr21:25789502-25791503~~chr21:26168596-26171705,
chr21:25789567-25791545~~chr21:26168542-26171800,
chr21:25850000-25875000~~chr21:26175000-26200000,
chr21:25875000-25900000~~chr21:26150000-26175000,
chr21:25875000-25900000~~chr21:26175000-26200000,
chr21:25880592-25882759~~chr21:26168595-26171726,
chr21:25880643-25882866~~chr21:26169947-26171806,
chr21:25880719-25882754~~chr21:26168603-26171485,
chr21:25880755-25882952~~chr21:26168541-26171786,
chr21:25880762-25882939~~chr21:26168567-26172542,
chr21:25880770-25883137~~chr21:26168491-26171741,
chr21:25880785-25882961~~chr21:26168597-26171877,
chr21:25880794-25882895~~chr21:26168600-26171765,
chr21:25880795-25883103~~chr21:26168579-26171699,
chr21:25880806-25883113~~chr21:26168567-26171752,
chr21:25880813-25882766~~chr21:26170075-26171770,
chr21:25880821-25883172~~chr21:26168566-26171735,
chr21:25880831-25882882~~chr21:26168509-26171714,
chr21:25880854-25882845~~chr21:26170145-26171780,
chr21:25880871-25883139~~chr21:26168536-26171703,
chr21:25880878-25883186~~chr21:26169836-26171640,
chr21:25880913-25882748~~chr21:26169335-26171730,
chr21:25880959-25882727~~chr21:26168566-26171728,
chr21:25881105-25882920~~chr21:26168579-26171721,
chr21:25886689-25887960~~chr21:26168542-26171691,
chr21:25894856-25897119~~chr21:26168541-26171786,
chr21:25895002-25896873~~chr21:26168572-26171752,
chr21:25895048-25897116~~chr21:26168461-26171694,
chr21:25895145-25896737~~chr21:26169947-26171806,
chr21:25895183-25896791~~chr21:26168600-26171765,
chr21:25895184-25896849~~chr21:26168597-26171877,
chr21:25895199-25896667~~chr21:26170075-26171770,
chr21:25895223-25896749~~chr21:26170145-26171780,
chr21:25925000-25950000~~chr21:26150000-26175000,
chr21:25950000-25975000~~chr21:26150000-26175000,
chr21:25975000-26000000~~chr21:26150000-26175000,
chr21:26025000-26050000~~chr21:26150000-26175000,
chr21:26031848-26033090~~chr21:26168677-26171722,
chr21:26050000-26075000~~chr21:26150000-26175000,
chr21:26150000-26175000~~chr21:26325000-26350000,
chr21:26150000-26175000~~chr21:26375000-26400000,
chr21:26150000-26175000~~chr21:26425000-26450000,
chr21:26150000-26175000~~chr21:26525000-26550000,
chr21:26150000-26175000~~chr21:26550000-26575000,
chr21:26150000-26175000~~chr21:26700000-26725000,
chr21:26150000-26175000~~chr21:26800000-26825000,
chr21:26150000-26175000~~chr21:26825000-26850000,
chr21:26150000-26175000~~chr21:27500000-27525000,
chr21:26168536-26171703~~chr21:26715160-26718522,
chr21:26168542-26171691~~chr21:26714717-26718289,
chr21:26168542-26171800~~chr21:26715396-26718303,
chr21:26168566-26171735~~chr21:26715280-26718256,
chr21:26168567-26172542~~chr21:26715356-26718205,
chr21:26168579-26171721~~chr21:26714841-26717171,
chr21:26168586-26171752~~chr21:26715190-26718539,
chr21:26168591-26172572~~chr21:26715252-26718261,
chr21:26175000-26200000~~chr21:26375000-26400000,
chr21:26175000-26200000~~chr21:26675000-26700000,
chr21:26175000-26200000~~chr21:26700000-26725000,
chr21:26175000-26200000~~chr21:27500000-27525000,
chr21:26175000-26200000~~chr21:28725000-28750000,
chr21:26175000-26200000~~chr21:29075000-29100000,
chr21:26177658-26178878~~chr21:26715348-26718310,