- Basic information
- CohesinDB ID: CDBP00415373
- Locus: chr21-26007390-26008630
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Data sourse: ENCSR230ZWH, GSE206145, GSE62063, GSE116344, ENCSR917QNE
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Cell type: Liver, RH4, HEK293T, Ramos
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: NIPBL,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 52%,
"7_Enh": 20%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, PAX7, NANOG, PGR, FOXA2, NKX2-2, CEBPA, PAF1, XBP1, ZBTB17, FOXA1, ZBTB33, HOXB13, ERG, YY1, NEUROD1, ATF3, ONECUT1, MYC, SMARCA4, ETS1, GATA4, RAD21, ZBTB44, PBX4, GRHL3, ARNT, RXRA, OTX2, ATF4, NKX2-1, PROX1, GABPA, MAX, MAFB, NKX3-1, CEBPG, CEBPB, NR2F2, CREB1, PIAS1, SCRT2, ETV1, MYOD1, PHOX2B, CTCF, RBM22, ELF3, SP1, BRD2, SPI1, BCL11A, AR, PAX3-FOXO1, IRF1, GATA6, GATA2, POU2F3, FLI1, JUND, BRD4, SCRT1, ZNF528, MRTFB, PDX1
- Target gene symbol (double-evidenced CRMs): MRPL39,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 40
- Number of somatic mutations (non-coding): 5
- Related genes and loops
- Related gene:
ENSG00000154719,
ENSG00000142192,
- Related loop:
chr21:25600000-25625000~~chr21:26000000-26025000,
chr21:25880833-25882973~~chr21:25999508-26002814,
chr21:25880878-25883186~~chr21:26000596-26002821,
chr21:25880879-25883157~~chr21:25999375-26002832,
chr21:25894872-25896862~~chr21:25999375-26002832,
chr21:25895093-25897256~~chr21:26000596-26002821,
chr21:25895184-25896718~~chr21:25999508-26002814,
chr21:26000000-26025000~~chr21:26325000-26350000,
chr21:26000000-26025000~~chr21:26700000-26725000,
chr21:26010694-26012200~~chr21:26715347-26718278,
chr21:26010769-26012247~~chr21:26715196-26718405,