- Basic information
- CohesinDB ID: CDBP00415380
- Locus: chr21-26019797-26021009
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Data sourse: GSE126634, GSE206145-GSE177045, GSE152721
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Cell type: MCF-7, HAP1
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: False
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 56%,
"4_Tx": 23%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ASCL1, GATA2, ZNF143, FOXA2, NKX2-2, POU5F1, SCRT2, AGO2, GRHL3, GTF2B, SCRT1, PRDM9, ERG3, EGR2, NKX3-1, ERG2, RBM22, HOXB13, ZFHX2, PDX1
- Target gene symbol (double-evidenced CRMs): MRPL39,APP
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 40
- Number of somatic mutations (non-coding): 5
- Related genes and loops