- Basic information
- CohesinDB ID: CDBP00415406
- Locus: chr21-26097068-26098116
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Data sourse: GSE111913, ENCSR000BLY, ENCSR404BPV, ShirahigeLab, ENCSR198ZYJ, ENCSR000EHX
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Cell type: Neurons-H1, RT-112, RPE, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: SMC3,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intragenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
68% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"5_TxWk": 68%,
"15_Quies": 17%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, CHD8, ZNF263, MYCN, PAF1, ZFX, XBP1, MAFF, ZBTB48, WT1, FOXA1, ZNF770, ERG3, YY1, RELA, ASCL1, NEUROD1, AHR, GATA4, OSR2, GR, ISL1, SP140, ZIC2, OTX2, GATA3, GATA1, RCOR1, HAND2, NR3C1, ZNF121, SCRT2, EZH2, ESR1, OCA2, C11orf30, PITX3, SETDB1, PHOX2B, JUN, RBM22, MAFK, CTCF, EP300, AR, TAF1, GATA2, REST, ZNF423, PHIP, SCRT1, TBX2, ZNF316
- Target gene symbol (double-evidenced CRMs): APP,MRPL39
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 56
- Number of somatic mutations (non-coding): 0
- Related genes and loops