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Basic information

CohesinDB ID: CDBP00415445

Locus: chr21-26199145-26200151

Data sourse: GSE115250, GSE101921, GSE206145-NatGen2015, GSE85526, GSE165895

Cell type: HMEC, Fibroblast, HEKn, TC-32, HFFc6

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: SA1,Rad21,SMC1,SA2,Mau2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intragenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 68% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 79%, "7_Enh": 11%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: SMC1A, FOXA2, NKX2-2, SMAD3, FOXA1, KDM1A, RELA, JUNB, RUNX2, GRHL3, HIF1A, ZNF487, SOX11, STAT3, MAFB, TP63, FOS, NKX3-1, RCOR1, MED1, NR3C1, MAF, PDX1, CEBPB, TEAD1, ZNF750, NFE2L2, TP73, NFKB1, JUN, MAFK, BHLHE40, AR, YAP1, MXI1, BRD4, SMC1, STAG2

Target gene symbol (double-evidenced CRMs): MRPL39,APP

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154719, ENSG00000142192,

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Deatailed information for cohesin site CDBP00415445