- Basic information
- CohesinDB ID: CDBP00415550
- Locus: chr21-26756401-26757018
-
Data sourse: GSE206145, GSE116344, GSE206145-NatGen2015
-
Cell type: RPE, Fibroblast, RH4
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: Mau2,Rad21,SA2
-
CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
-
Chromatin annotation:
"15_Quies": 85%,
"7_Enh": 9%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: PGR, FOXA2, TOP2A, SOX2, HNF1A, GTF2B, SMAD3, XBP1, FOXA1, HOXB13, YY1, NEUROD1, RUNX2, CHD7, LHX2, PBX4, GRHL3, OTX2, NFE2, MED1, NR3C1, MYOG, CEBPB, NR2F2, NFE2L2, ZHX2, TCF12, SP1, AR, GATA2, BRD4, MRTFB
- Target gene symbol (double-evidenced CRMs): LINC00113,ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 3
- Related genes and loops