- Basic information
- CohesinDB ID: CDBP00415554
- Locus: chr21-26765908-26766700
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Data sourse: GSE98367, GSE206145, GSE120943, GSE83726, GSE116344
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Cell type: RPE, RH4, Monocytes, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Rad21,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 93%,
"5_TxWk": 3%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RELA, GATA6, POU2F2, SMC1A, NME2, ZFX, RAD21, CTCF, OCA2, CLOCK, DDX5, ZSCAN4, ZNF143, GSPT2
- Target gene symbol (double-evidenced CRMs): ADAMTS5,LINC00113
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 10
- Related genes and loops
- Related gene:
ENSG00000154736,
ENSG00000225298,
- Related loop:
chr21:26750000-26775000~~chr21:26950000-26975000,
chr21:26750000-26775000~~chr21:27700000-27725000,
chr21:26750000-26775000~~chr21:28025000-28050000,
chr21:26750000-26775000~~chr21:28325000-28350000,
chr21:26750000-26775000~~chr21:28725000-28750000,
chr21:26750000-26775000~~chr21:28925000-28950000,
chr21:26768397-26771044~~chr21:26840431-26841710,
chr21:26768427-26770708~~chr21:26842624-26843855,
chr21:26768475-26770735~~chr21:27700023-27702186,
chr21:26768631-26771060~~chr21:27700355-27702199,
chr21:26768665-26770424~~chr21:27699913-27702170,
chr21:26768676-26770716~~chr21:26833331-26835927,
chr21:26768928-26771044~~chr21:26833230-26835582,
chr21:26768979-26770511~~chr21:27700287-27702114,
chr21:26768979-26770792~~chr21:27213020-27214262,
chr21:26769208-26770436~~chr21:27700042-27701914,
chr21:26769270-26770477~~chr21:27700358-27702051,