- Basic information
- CohesinDB ID: CDBP00415581
- Locus: chr21-26854502-26857883
-
Data sourse: GSE105004, GSE67783, GSE86191, GSE98367, GSE206145, GSE206145-NatGen2015, GSE120943, GSE83726, GSE116344, GSE108869
-
Cell type: RPE, Fibroblast, HCT-116, Monocytes, HEK293T, RH4, HeLa-S3, HeLa, HSPC, Macrophage
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 3% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.889
- Subunit: SA1,Rad21,SMC1,SA2,SMC3
-
CTCF binding site: CTCF
CTCF motif: True
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
-
Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
41% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): True
-
Chromatin annotation:
"15_Quies": 72%,
"14_ReprPCWk": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
-
Co-bound Transcriptional factors: CREBBP, MAF, CEBPB, SMC1A, CHD8, NME2, ESR1, TP63
- Target gene symbol (double-evidenced CRMs): ADAMTS5,LINC00113
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 42
- Related genes and loops
- Related gene:
ENSG00000154736,
ENSG00000225298,
- Related loop:
chr21:23400000-23425000~~chr21:26825000-26850000,
chr21:25025000-25050000~~chr21:26825000-26850000,
chr21:25375000-25400000~~chr21:26825000-26850000,
chr21:25600000-25625000~~chr21:26825000-26850000,
chr21:25625000-25650000~~chr21:26825000-26850000,
chr21:25725000-25750000~~chr21:26825000-26850000,
chr21:25875000-25900000~~chr21:26825000-26850000,
chr21:26150000-26175000~~chr21:26825000-26850000,
chr21:26700000-26725000~~chr21:26825000-26850000,
chr21:26725000-26750000~~chr21:26825000-26850000,
chr21:26825000-26850000~~chr21:26925000-26950000,
chr21:26825000-26850000~~chr21:27550000-27575000,
chr21:26825000-26850000~~chr21:27675000-27700000,
chr21:26825000-26850000~~chr21:27700000-27725000,
chr21:26825000-26850000~~chr21:28025000-28050000,
chr21:26825000-26850000~~chr21:28050000-28075000,
chr21:26825000-26850000~~chr21:28200000-28225000,
chr21:26825000-26850000~~chr21:28225000-28250000,
chr21:26825000-26850000~~chr21:28325000-28350000,
chr21:26825000-26850000~~chr21:28425000-28450000,
chr21:26825000-26850000~~chr21:28500000-28525000,
chr21:26825000-26850000~~chr21:28525000-28550000,
chr21:26825000-26850000~~chr21:28575000-28600000,
chr21:26825000-26850000~~chr21:28625000-28650000,
chr21:26825000-26850000~~chr21:28725000-28750000,
chr21:26825000-26850000~~chr21:28750000-28775000,
chr21:26825000-26850000~~chr21:28925000-28950000,
chr21:26825000-26850000~~chr21:28950000-28975000,
chr21:26825000-26850000~~chr21:30175000-30200000,
chr21:26848648-26851445~~chr21:27564056-27565671,
chr21:26848648-26851445~~chr21:27700287-27702114,
chr21:26848655-26851362~~chr21:27563683-27565992,
chr21:26848655-26851362~~chr21:27673391-27674734,
chr21:26848655-26851362~~chr21:27700015-27702372,
chr21:26848657-26851571~~chr21:27563649-27565742,
chr21:26848657-26851571~~chr21:27700129-27702131,
chr21:26848663-26851399~~chr21:27564063-27565968,
chr21:26848663-26851399~~chr21:27700279-27702131,
chr21:26848676-26851554~~chr21:27700282-27702347,
chr21:26848685-26851208~~chr21:27700325-27702096,
chr21:26848686-26851632~~chr21:27563536-27566212,
chr21:26848686-26851632~~chr21:27699551-27702135,
chr21:26848688-26851432~~chr21:27700355-27702199,
chr21:26848688-26851432~~chr21:27802305-27803923,
chr21:26848701-26852142~~chr21:27474660-27477802,
chr21:26848701-26852142~~chr21:27699511-27702311,
chr21:26848717-26851115~~chr21:27700284-27702122,
chr21:26848717-26851115~~chr21:27802133-27803841,
chr21:26848717-26851211~~chr21:27700526-27702055,
chr21:26848717-26851211~~chr21:27802381-27803695,
chr21:26848718-26851536~~chr21:27700320-27702132,
chr21:26848727-26851343~~chr21:27700565-27702018,
chr21:26848729-26851350~~chr21:27700318-27702132,
chr21:26848733-26851211~~chr21:27700246-27702059,
chr21:26848735-26851318~~chr21:27564094-27565665,
chr21:26848735-26851318~~chr21:27700350-27702114,
chr21:26848735-26852148~~chr21:27700351-27702121,
chr21:26848739-26851655~~chr21:27563988-27566020,
chr21:26848739-26851655~~chr21:27700076-27702211,
chr21:26848745-26851720~~chr21:27700358-27702051,
chr21:26848748-26851651~~chr21:27563895-27566084,
chr21:26848748-26851651~~chr21:27699952-27702148,
chr21:26848749-26851118~~chr21:27700496-27701999,
chr21:26848750-26851648~~chr21:27700517-27702048,
chr21:26848751-26851646~~chr21:27563920-27566182,
chr21:26848751-26851646~~chr21:27700023-27702186,
chr21:26848757-26851632~~chr21:27563925-27566163,
chr21:26848757-26851632~~chr21:27700291-27702152,
chr21:26848761-26852116~~chr21:27465346-27467252,
chr21:26848761-26852116~~chr21:27700300-27702127,
chr21:26848763-26851113~~chr21:27700525-27701999,
chr21:26848765-26851527~~chr21:27699929-27702131,
chr21:26848765-26851527~~chr21:27802176-27803976,
chr21:26848770-26851390~~chr21:27564032-27565789,
chr21:26848770-26851390~~chr21:27699952-27702098,
chr21:26848770-26851390~~chr21:27802290-27803924,
chr21:26848785-26851026~~chr21:27564188-27565622,
chr21:26848785-26851026~~chr21:27700507-27702020,
chr21:26848803-26851219~~chr21:27700394-27702179,
chr21:26848804-26851538~~chr21:27700287-27702107,
chr21:26848830-26851638~~chr21:27700281-27702128,
chr21:26848834-26851460~~chr21:27563907-27565665,
chr21:26848834-26851460~~chr21:27700290-27702123,
chr21:26848856-26851244~~chr21:27700305-27702116,
chr21:26848864-26851333~~chr21:27700333-27701995,
chr21:26848867-26851805~~chr21:27700506-27702101,
chr21:26848882-26851252~~chr21:27700303-27702035,
chr21:26848931-26851381~~chr21:27700288-27701996,
chr21:26848935-26851041~~chr21:27700220-27701917,
chr21:26848935-26851073~~chr21:27700474-27701901,
chr21:26848936-26851071~~chr21:27700526-27701775,
chr21:26848936-26851075~~chr21:27564009-27565590,
chr21:26848936-26851075~~chr21:27700042-27701914,
chr21:26848947-26851347~~chr21:27564022-27565633,
chr21:26848947-26851347~~chr21:27700028-27702259,
chr21:26848947-26851347~~chr21:27802087-27803810,
chr21:26848955-26851551~~chr21:27699963-27702208,
chr21:26848955-26851551~~chr21:27758404-27760678,
chr21:26848956-26852143~~chr21:27700277-27702128,
chr21:26848956-26852143~~chr21:27802108-27803785,
chr21:26848960-26851060~~chr21:27700563-27701854,
chr21:26849043-26851569~~chr21:27564132-27565614,
chr21:26849043-26851569~~chr21:27700335-27702088,
chr21:26849043-26851569~~chr21:27758641-27759952,
chr21:26849049-26852110~~chr21:27564063-27565789,
chr21:26849049-26852110~~chr21:27699913-27702170,
chr21:26849049-26852110~~chr21:27758357-27760293,
chr21:26849232-26851602~~chr21:27700517-27701777,
chr21:26849251-26851658~~chr21:27699991-27702131,
chr21:26849441-26851499~~chr21:27700289-27702138,
chr21:26849452-26851114~~chr21:27700473-27702088,
chr21:26849486-26851137~~chr21:27700482-27702087,
chr21:26849487-26851382~~chr21:27700376-27702045,
chr21:26849494-26851554~~chr21:27700337-27702131,
chr21:26849499-26851723~~chr21:27700510-27702123,
chr21:26850000-26875000~~chr21:26950000-26975000,
chr21:26850000-26875000~~chr21:27025000-27050000,
chr21:26850000-26875000~~chr21:27075000-27100000,
chr21:26850000-26875000~~chr21:27175000-27200000,
chr21:26850000-26875000~~chr21:27200000-27225000,
chr21:26850000-26875000~~chr21:27225000-27250000,
chr21:26850000-26875000~~chr21:27300000-27325000,
chr21:26850000-26875000~~chr21:27350000-27375000,
chr21:26850000-26875000~~chr21:27400000-27425000,
chr21:26850000-26875000~~chr21:27425000-27450000,
chr21:26850000-26875000~~chr21:27450000-27475000,
chr21:26850000-26875000~~chr21:27475000-27500000,
chr21:26850000-26875000~~chr21:27550000-27575000,
chr21:26850000-26875000~~chr21:27575000-27600000,
chr21:26850000-26875000~~chr21:27650000-27675000,
chr21:26850000-26875000~~chr21:27675000-27700000,
chr21:26850000-26875000~~chr21:27700000-27725000,
chr21:26850000-26875000~~chr21:28025000-28050000,
chr21:26850000-26875000~~chr21:28050000-28075000,
chr21:26850000-26875000~~chr21:28300000-28325000,
chr21:26850000-26875000~~chr21:28325000-28350000,
chr21:26850000-26875000~~chr21:28500000-28525000,
chr21:26850000-26875000~~chr21:28550000-28575000,
chr21:26850000-26875000~~chr21:28725000-28750000,
chr21:26850000-26875000~~chr21:28750000-28775000,
chr21:26850000-26875000~~chr21:28925000-28950000,