- Basic information
- CohesinDB ID: CDBP00415593
- Locus: chr21-26917803-26919602
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Data sourse: ENCSR000EFJ, GSE138405, ENCSR000HPG, GSE206145-NatGen2015, ENCSR000EDE, GSE126990, GSE108869, ENCSR000ECS, GSE165895
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Cell type: Hela-Kyoto, Fibroblast, HeLa-S3, IMR-90, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 5% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.944
- Subunit: SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 62%,
"5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: NFYB, FOXO1, PGR, FOXA2, SOX2, AFF4, SMAD3, MAFF, FOXA1, SRF, BAHD1, HIC1, HOXB13, SMARCC1, HOXC5, ERG, ZNF384, JUNB, MYC, GATA4, RAD21, DAXX, PBX4, ARNT, GRHL3, PRDM9, STAT3, PBX3, MAX, NKX3-1, FOS, TLE3, NR3C1, CEBPB, NR2F2, CREB1, TCF7L2, PIAS1, NFE2L2, ZNF334, JUN, MAFK, EP300, BAF155, BHLHE40, AR, GATA2, RFX5, ZHX1, BRD4, JUND, SMC3, ELL2, BRCA1, FOSL2
- Target gene symbol (double-evidenced CRMs): ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 29
- Number of somatic mutations (non-coding): 1
- Related genes and loops