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Basic information

CohesinDB ID: CDBP00415594

Locus: chr21-26919999-26920614

Data sourse: ENCSR000EDE, ENCSR230ZWH, ENCSR000ECS, ENCSR917QNE

Cell type: Liver, HeLa-S3

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 1% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SMC3,Rad21

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: TES

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: False ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 70%, "5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: PGR, POU2F2, PPARG, FOXA2, CEBPA, NKX2-2, CHD2, XBP1, FOXA1, ZBTB33, HOXB13, TBP, HNF4G, ERG, YY1, RELA, ATF3, ONECUT1, RUNX2, GATA4, RAD21, PBX4, GRHL3, HIF1A, RXRA, OTX2, GABPA, STAT3, MAX, ZNF143, FOS, MED1, NR3C1, CEBPB, NR2F2, EBF3, JUN, SP1, BAF155, EP300, HNF4A, AR, REST, GATA2, RFX5, EGR1, JUND, BRD4, PDX1

Target gene symbol (double-evidenced CRMs): ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 1

Number of somatic mutations (non-coding): 0

Related genes and loops

Related gene: ENSG00000154736,

Tools:

Assay

refGene

Ruler

Cohesin site CDBP00415594

CDBP00415594 regulated genes

Related cohesin loop

Deatailed information for cohesin site CDBP00415594

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