- Basic information
- CohesinDB ID: CDBP00415594
- Locus: chr21-26919999-26920614
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Data sourse: ENCSR000EDE, ENCSR230ZWH, ENCSR000ECS, ENCSR917QNE
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Cell type: Liver, HeLa-S3
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 1% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: SMC3,Rad21
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: TES
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
40% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 70%,
"5_TxWk": 16%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: PGR, POU2F2, PPARG, FOXA2, CEBPA, NKX2-2, CHD2, XBP1, FOXA1, ZBTB33, HOXB13, TBP, HNF4G, ERG, YY1, RELA, ATF3, ONECUT1, RUNX2, GATA4, RAD21, PBX4, GRHL3, HIF1A, RXRA, OTX2, GABPA, STAT3, MAX, ZNF143, FOS, MED1, NR3C1, CEBPB, NR2F2, EBF3, JUN, SP1, BAF155, EP300, HNF4A, AR, REST, GATA2, RFX5, EGR1, JUND, BRD4, PDX1
- Target gene symbol (double-evidenced CRMs): ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 1
- Number of somatic mutations (non-coding): 0
- Related genes and loops
- Related gene:
ENSG00000154736,
- Related loop:
chr21:17450000-17475000~~chr21:26925000-26950000,
chr21:25650000-25675000~~chr21:26925000-26950000,
chr21:26825000-26850000~~chr21:26925000-26950000,
chr21:26900000-26925000~~chr21:27200000-27225000,
chr21:26900000-26925000~~chr21:27550000-27575000,
chr21:26900000-26925000~~chr21:28325000-28350000,
chr21:26925000-26950000~~chr21:27100000-27125000,
chr21:26925000-26950000~~chr21:27200000-27225000,
chr21:26925000-26950000~~chr21:27300000-27325000,
chr21:26925000-26950000~~chr21:27375000-27400000,
chr21:26925000-26950000~~chr21:27550000-27575000,