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Basic information

CohesinDB ID: CDBP00415608

Locus: chr21-26972162-26972628

Data sourse: GSE111537, GSE98367

Cell type: OCI-AML-3, Macrophage

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 0% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.978

Subunit: SA2,SMC1

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 40% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 52%, "14_ReprPCWk": 30%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: RUNX1, SKI, SMC1A, CEBPA, TOP2A, MEIS1, ZFX, RUNX1T1, STAT1, FOXA1, MLLT3, MEF2C, CDK9, PBX2, KDM1A, ERG, RELA, TCF4, HIF1A, MECOM, STAT3, SPIB, CDK8, VDR, TRIM28, MYB, KMT2A, EVI1, STAT5A, ELF3, CTCF, MAFK, SPI1, TCF12, NR4A1, RXR, TRIM24, FLI1, HOXA9, BRD4, RELB, KMT2B

Target gene symbol (double-evidenced CRMs): ADAMTS1,LINC00113

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 4

Related genes and loops

Related gene: ENSG00000154734, ENSG00000225298,

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Deatailed information for cohesin site CDBP00415608