- Basic information
- CohesinDB ID: CDBP00415634
- Locus: chr21-27101424-27102041
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Data sourse: ENCSR000EDE, GSE206145-NatGen2015, ENCSR000HPG, ENCSR000ECS
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Cell type: HeLa-S3, Fibroblast, IMR-90
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.967
- Subunit: SA1,Rad21,SA2,Mau2,SMC3
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 89%,
"9_Het": 5%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: MED1, RELA, ZNF257, NR3C1, CEBPB, BRD4, STAT3, CTCF, EP300
- Target gene symbol (double-evidenced CRMs): ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 2
- Related genes and loops
- Related gene:
ENSG00000154736,
- Related loop:
chr21:26850000-26875000~~chr21:27075000-27100000,
chr21:26925000-26950000~~chr21:27100000-27125000,
chr21:27075000-27100000~~chr21:27550000-27575000,
chr21:27075000-27100000~~chr21:30300000-30325000,
chr21:27100000-27125000~~chr21:27200000-27225000,
chr21:27100000-27125000~~chr21:27225000-27250000,
chr21:27100000-27125000~~chr21:27300000-27325000,
chr21:27100000-27125000~~chr21:27350000-27375000,
chr21:27100000-27125000~~chr21:27450000-27475000,
chr21:27100000-27125000~~chr21:27475000-27500000,
chr21:27100000-27125000~~chr21:27550000-27575000,
chr21:27100000-27125000~~chr21:28325000-28350000,
chr21:27100000-27125000~~chr21:28425000-28450000,