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Basic information

CohesinDB ID: CDBP00415636

Locus: chr21-27108104-27108760

Data sourse: GSE138405, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, ENCSR000EHX, GSE138105, GSE126990

Cell type: RPE, Hela-Kyoto, Fibroblast, SLK, SK-N-SH

DNA Sequence of binding site: UCSC hg38

Cohesin category

Peak occupancy ratio: 3% samples have this site.

Cell specificity (0: conserved, 1: cell type specific): 0.944

Subunit: Mau2,SA1,Rad21,SA2

CTCF binding site: non-CTCF CTCF motif: False

Genomic location: Intergenic

3D genome

TAD boundary: non-Boundary

Chromatin hubs: Hub

Hi-C loops: True Hi-ChIP loops: True ChIA-PET loops: True

Compartment: 38% Hi-C samples shows Compartment A

Cis-regulatory elements

Enhancer (Fantom5): non-Enhancer

Super enhancer (SEdb): False

Chromatin annotation: "15_Quies": 76%, "7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).

Co-bound Transcriptional factors: FOXO1, SMC1A, MYCN, CHD2, SOX2, SIN3A, HNF1A, MAFF, FOXF1, ZNF205, ZBTB33, SMARCC1, TWIST1, HOXC5, MEF2A, RELA, CREBBP, KDM1A, YY1, NFIC, GATA4, RAD21, LHX2, ISL1, PRDM1, RXRA, GATA3, STAT3, PBX3, MAX, FOXM1, FOS, TP63, RCOR1, UBN1, HAND2, NR3C1, NR2F2, TP53, ESR1, TP73, PITX3, EBF3, ZHX2, TCF12, EP300, MAFK, GATA2, BRD4, JUND, TEAD4, FOSL2

Target gene symbol (double-evidenced CRMs): ADAMTS5

Function elements

Human SNPs: .

Number of somatic mutations (coding): 0

Number of somatic mutations (non-coding): 10

Related genes and loops

Related gene: ENSG00000154736,

eachgene

Deatailed information for cohesin site CDBP00415636