- Basic information
- CohesinDB ID: CDBP00415638
- Locus: chr21-27111585-27112109
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Data sourse: GSE138405, GSE206145-NatGen2015
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Cell type: Hela-Kyoto, Fibroblast
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 0% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.978
- Subunit: Mau2,SA2
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
38% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 80%,
"7_Enh": 12%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXO1, NANOG, FOXA2, FOXA1, ZNF205, SRF, HOXB13, HOXC5, ERG, JUNB, NFIC, GATA4, RAD21, DAXX, GRHL3, PBX4, NKX2-1, GATA3, OTX2, STAT3, FOXM1, MAX, NKX3-1, FOS, PBX3, NR3C1, CEBPB, CREB1, ESR1, GRHL2, PHOX2B, JUN, TCF12, ZHX2, EP300, BAF155, AR, SIX2, HSF1, BRD4, FOXP1, TEAD4, PDX1
- Target gene symbol (double-evidenced CRMs): ADAMTS5
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 4
- Related genes and loops
- Related gene:
ENSG00000154736,
- Related loop:
chr21:26925000-26950000~~chr21:27100000-27125000,
chr21:27100000-27125000~~chr21:27200000-27225000,
chr21:27100000-27125000~~chr21:27225000-27250000,
chr21:27100000-27125000~~chr21:27300000-27325000,
chr21:27100000-27125000~~chr21:27350000-27375000,
chr21:27100000-27125000~~chr21:27450000-27475000,
chr21:27100000-27125000~~chr21:27475000-27500000,
chr21:27100000-27125000~~chr21:27550000-27575000,
chr21:27100000-27125000~~chr21:28325000-28350000,
chr21:27100000-27125000~~chr21:28425000-28450000,