- Basic information
- CohesinDB ID: CDBP00415659
- Locus: chr21-27189506-27191386
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Data sourse: ENCSR000BTU, GSE86191, GSE138405, ENCSR000BLY, GSE206145, GSE206145-NatGen2015, ENCSR000EDE, GSE138105, GSE126990
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Cell type: Hela-Kyoto, Fibroblast, HCT-116, HEK293T, SLK, Ishikawa, HeLa-S3, SK-N-SH
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.911
- Subunit: SA1,Rad21,SA2
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
39% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 89%,
"7_Enh": 7%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: RUNX1, TRP47, NANOG, PGR, SMARCA2, CEBPA, TEAD4, XBP1, ZBTB48, DUX4, STAT1, FOXA1, SRF, YY2, HOXB13, TWIST1, HNF4G, ERG, HOXC5, RELA, YY1, MEF2A, SMARCC1, RUNX2, NFIC, MYC, RAD21, ISL1, ARNT, HIF1A, SOX11, PBX4, RXRA, GATA3, GABPA, STAT3, MAX, PBX3, NKX3-1, FOS, FOXM1, UBN1, MED1, ARNTL, TLE3, NR3C1, ZNF750, CEBPB, ESRRA, CREB1, PIAS1, TCF7L2, KDM5B, ETV1, ESR1, EBF3, PHOX2B, TCF12, NUP98-HOXA9, EP300, BAF155, AR, GATA2, ZHX1, NOTCH3, BRD4, JUND, FOXP1, SMC3, TFAP2C, FOSL2
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 19
- Related genes and loops