- Basic information
- CohesinDB ID: CDBP00415675
- Locus: chr21-27246186-27247365
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Data sourse: GSE165895, GSE206145-NatGen2015, GSE68388, GSE138105
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Cell type: SLK, Fibroblast, HuCC-T1, HFFc6
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 2% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.956
- Subunit: Mau2,Rad21,SA2,SMC1
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CTCF binding site: non-CTCF
CTCF motif: False
- Genomic location: Intergenic
- 3D genome
- TAD boundary: Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: False
ChIA-PET loops: True
- Compartment:
39% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): non-Enhancer
- Super enhancer (SEdb): False
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Chromatin annotation:
"15_Quies": 82%,
"7_Enh": 8%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: FOXA2, NKX2-2, POU5F1, SMAD3, MLLT3, HOXC5, RELA, JUNB, RUNX2, GATA4, GRHL3, MAX, FOS, MED1, NR3C1, CEBPB, TP53, JUN, TCF12, ZHX2, BRD4, JUND, PDX1, FOSL2
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 14
- Related genes and loops
- Related gene:
ENSG00000154734,
- Related loop:
chr21:26850000-26875000~~chr21:27225000-27250000,
chr21:27100000-27125000~~chr21:27225000-27250000,
chr21:27225000-27250000~~chr21:27350000-27375000,
chr21:27225000-27250000~~chr21:27450000-27475000,
chr21:27225000-27250000~~chr21:27550000-27575000,
chr21:27225000-27250000~~chr21:27675000-27700000,
chr21:27225000-27250000~~chr21:28350000-28375000,
chr21:27250000-27275000~~chr21:27425000-27450000,
chr21:27250000-27275000~~chr21:27550000-27575000,
chr21:27250000-27275000~~chr21:27675000-27700000,
chr21:27250000-27275000~~chr21:28325000-28350000,