- Basic information
- CohesinDB ID: CDBP00415719
- Locus: chr21-27421200-27426298
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Data sourse: ENCSR000BLD, ENCSR230ZWH, ENCSR000BLY, GSE105028, GSE108869, GSE165895, ENCSR000EFJ, ENCSR000BTU, GSE67783, GSE138405, GSE206145-NatGen2015, GSE138105, GSE116344, GSE76815, GSE206145, ENCSR000ECE, ENCSR000EHX, GSE97394, ENCSR000HPG, GSE68388, GSE83726, GSE126990, GSE64758
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Cell type: RPE, H1-hESC, Fibroblast, Hela-Kyoto, RH4, SLK, Ishikawa, HeLa-S3, HUES64, IMR-90, HSPC, SK-N-SH, Liver, HFFc6, HuCC-T1, H9-hESC
- DNA Sequence of binding site:
UCSC hg38
- Cohesin category
- Peak occupancy ratio: 16% samples have this site.
- Cell specificity (0: conserved, 1: cell type specific): 0.822
- Subunit: NIPBL,SA1,Rad21,SMC1,SA2,Mau2,SMC3
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CTCF binding site: CTCF
CTCF motif: False
- Genomic location: TSS,TES,Intragenic
- 3D genome
- TAD boundary: non-Boundary
- Chromatin hubs: Hub
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Hi-C loops: True
Hi-ChIP loops: True
ChIA-PET loops: True
- Compartment:
36% Hi-C samples shows Compartment A
- Cis-regulatory elements
- Enhancer (Fantom5): Enhancer
- Super enhancer (SEdb): True
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Chromatin annotation:
"15_Quies": 50%,
"7_Enh": 29%,
Note: The percentage represent how many of the 127 Roadmap datasets show the indicated state (top 2).
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Co-bound Transcriptional factors: ZBTB48, PGR
- Target gene symbol (double-evidenced CRMs): ADAMTS1
- Function elements
- Human SNPs: .
- Number of somatic mutations (coding): 0
- Number of somatic mutations (non-coding): 50
- Related genes and loops